Estradiol Hemihydrate

Name: Estradiol Hemihydrate
Brand: Vaqora Chemicals
SKU: VQ-030568

About Estradiol Hemihydrate

Estradiol Hemihydrate (CAS 35380-71-3) is a high-purity reference standard of Estradiol offered by Vaqora Chemicals. The compound has the formula C36H50O5, corresponding to a molecular weight of 562.8 g/mol. Alternative names: 17b-Estradiol and beta-Estradiol semihydrate.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 6 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Estradiol standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Estradiol Hemihydrate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Estradiol

View every impurity, metabolite and intermediate we list for Estradiol.

Estradiol impurities

Specifications & identifiers

Chemical identifiers
Product name	Estradiol Hemihydrate
Catalogue No.	VQ-030568
CAS Number	35380-71-3
IUPAC name	bis((8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol);hydrate
Molecular formula	C₃₆H₅₀O₅
Molecular weight	562.8 g/mol
Exact mass	562.3658
Grade	Reference Standard
HSN code	38229090
InChIKey	ZVVGLAMWAQMPDR-WVEWYJOQSA-N
SMILES	C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)O.C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C3C=CC(=C4)O.O
PubChem CID	154274

Physical properties
Physical form	Solid
H-bond donors / acceptors	5 / 5
TPSA	81.9 Å²
Synonyms	17b-Estradiol, beta-Estradiol semihydrate, beta-Estradiol hemihydrate, Estra-1,3,5(10)-triene-3,17beta-diol hydrate (2:1), Estra-1,3,5(10)-triene-3,17-diol (17beta)-, hydrate (2:1), Estra-1(10),2,4-triene-3,17beta-diol--water (2/1)

Safety & hazard information (GHS)

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H350May cause cancer
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H362May cause harm to breast-fed children
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P263, P264, P270, P273, P280, P318, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Estradiol Hemihydrate?

The CAS Registry Number of Estradiol Hemihydrate is 35380-71-3. It is also known as 17b-Estradiol, beta-Estradiol semihydrate, beta-Estradiol hemihydrate.

What is the molecular formula and molecular weight of Estradiol Hemihydrate?

Estradiol Hemihydrate has the molecular formula C36H50O5 and a molecular weight of 562.8 g/mol.

What is Estradiol Hemihydrate used for?

Estradiol Hemihydrate is supplied as a characterised reference material related to Estradiol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Estradiol Hemihydrate can I order?

We supply Estradiol Hemihydrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Estradiol Hemihydrate?

Yes. Every lot of Estradiol Hemihydrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Estradiol Hemihydrate be shipped internationally?

Yes. Estradiol Hemihydrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.