Estriol

Name: Estriol
Brand: Vaqora Chemicals
SKU: VQ-007472

About Estriol

Listed under CAS 50-27-1, Estriol is a high-purity reference standard of Estriol available from Vaqora Chemicals. The compound has the formula C18H24O3, corresponding to a molecular weight of 288.4 g/mol. Its systematic (IUPAC) name is (8R,9S,13S,14S,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol. Alternative names: Acifemine and Colpogyn.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Estriol, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Estriol

View every impurity, metabolite and intermediate we list for Estriol.

Estriol impurities

Specifications & identifiers

Chemical identifiers
Product name	Estriol
Catalogue No.	VQ-007472
CAS Number	50-27-1
IUPAC name	(8R,9S,13S,14S,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol
Molecular formula	C₁₈H₂₄O₃
Molecular weight	288.4 g/mol
Exact mass	288.1725
Grade	Reference Standard
HSN code	38229090
InChIKey	PROQIPRRNZUXQM-ZXXIGWHRSA-N
SMILES	C[C@]12CC[C@H]3[C@H]([C@@H]1C[C@H]([C@@H]2O)O)CCC4=C3C=CC(=C4)O
PubChem CID	5756

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	3 / 3
TPSA	60.7 Å²
Synonyms	(16alpha,17beta)-Estra-1,3,5[10]-triene-3,16,17-triol, Acifemine, Colpogyn, Destriol, Ovesterin, Ovestin, Tridestrin, Tricovex, Oestriol, Trihydroxyestrin, Aacifemine, Estratriol

Safety & hazard information (GHS)

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H350May cause cancer
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H362May cause harm to breast-fed children
H372Causes damage to organs through prolonged or repeated exposure
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P263, P264, P270, P273, P280, P318, P319, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 50-27-1

Estriol, 97%

CAS: 50-27-1
Formula: C₁₈H₂₄O₃
MW: 288.4 g/mol

VQ-003820

Frequently asked questions

What is the CAS number of Estriol?

The CAS Registry Number of Estriol is 50-27-1. It is also known as (16alpha,17beta)-Estra-1,3,5[10]-triene-3,16,17-triol, Acifemine, Colpogyn.

What is the molecular formula and molecular weight of Estriol?

Estriol has the molecular formula C18H24O3 and a molecular weight of 288.4 g/mol. Its IUPAC name is (8R,9S,13S,14S,16R,17R)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,16,17-triol.

What is Estriol used for?

Estriol is supplied as a characterised reference material related to Estriol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Estriol can I order?

We supply Estriol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Estriol?

Yes. Every lot of Estriol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Estriol be shipped internationally?

Yes. Estriol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.