Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrob… 136285-65-9

Name: Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate
Brand: Vaqora Chemicals
SKU: VQ-040897

About Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate

Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate is an impurity of Apremilast carrying the CAS registry number 136285-65-9. Formula C14H18N2O6, molecular weight 310.3 g/mol. Its systematic (IUPAC) name is ethyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-nitrobenzoate. It is also known as ethyl 2-t-butoxycarbonylamino-3-nitrobenzoate or Candesartan ester intermediate C3.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Apremilast, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Apremilast

View every impurity, metabolite and intermediate we list for Apremilast.

Apremilast impurities

Specifications & identifiers

Chemical identifiers
Product name	Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate
Catalogue No.	VQ-040897
CAS Number	136285-65-9
IUPAC name	ethyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-nitrobenzoate
Molecular formula	C₁₄H₁₈N₂O₆
Molecular weight	310.3 g/mol
Exact mass	310.1165
Grade	Reference Standard
HSN code	38229090
InChIKey	NYCBXLQKKUBOGV-UHFFFAOYSA-N
SMILES	CCOC(=O)C1=C(C(=CC=C1)[N+](=O)[O-])NC(=O)OC(C)(C)C
PubChem CID	12018930

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	1 / 6
TPSA	110 Å²
Synonyms	2-[1.1-dimethyl ethyl ethoxy carbonyl]amino-3-nitro benzoic acid ethyl ester, ethyl 2-[[(1,1-dimethylethoxy)carbonyl]amino]-3-nitrobenzoate, ethyl 2-t-butoxycarbonylamino-3-nitrobenzoate, Ethyl 2-[(t-butoxycarbonyl)amino]-3-nitrobenzoate, Candesartan ester intermediate C3, Ethyl 2-(Boc-amino)-3-nitrobenzoate, 2-[1.1-dimethyl ethyl ethoxy carbonyl]amino-3-nitro benzoic acid Ethyl Ester ( C3 ), ethyl 2 -t-butoxycarbonylamino-3-nitrobenzoate, Ethyl-2-(tertiary butoxy carbonyl aMino)-3-nitro benzoate, Benzoicacid, 2-[[(1, 1-diMethylethoxy)carbonyl]aMino]-3-nitro-, ethyl ester

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate?

The CAS Registry Number of Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate is 136285-65-9. It is also known as 2-[1.1-dimethyl ethyl ethoxy carbonyl]amino-3-nitro benzoic acid ethyl ester, ethyl 2-[[(1,1-dimethylethoxy)carbonyl]amino]-3-nitrobenzoate, ethyl 2-t-butoxycarbonylamino-3-nitrobenzoate.

What is the molecular formula and molecular weight of Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate?

Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate has the molecular formula C14H18N2O6 and a molecular weight of 310.3 g/mol. Its IUPAC name is ethyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-nitrobenzoate.

What is Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate used for?

Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate is supplied as a characterised reference material related to Apremilast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate can I order?

We supply Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate?

Yes. Every lot of Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate be shipped internationally?

Yes. We export Ethyl 2-((tert-butoxycarbonyl)amino)-3-nitrobenzoate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.