Ethyl 2,2-dichloro-3-oxobutanoate

Name: Ethyl 2,2-dichloro-3-oxobutanoate
Brand: Vaqora Chemicals
SKU: VQ-038420

About Ethyl 2,2-dichloro-3-oxobutanoate

Listed under CAS 6134-66-3, Ethyl 2,2-dichloro-3-oxobutanoate is an impurity of Febuxostat available from Vaqora Chemicals. The compound has the formula C6H8Cl2O3, corresponding to a molecular weight of 199.03 g/mol. Common synonyms include Ethyl-2,2-Dichloro Acetoacetate and Ethyl 2,2-dichloroacetoacetate.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Febuxostat, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Ethyl 2,2-dichloro-3-oxobutanoate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Febuxostat

View every impurity, metabolite and intermediate we list for Febuxostat.

Febuxostat impurities

Specifications & identifiers

Chemical identifiers
Product name	Ethyl 2,2-dichloro-3-oxobutanoate
Catalogue No.	VQ-038420
CAS Number	6134-66-3
IUPAC name	ethyl 2,2-dichloro-3-oxobutanoate
Molecular formula	C₆H₈Cl₂O₃
Molecular weight	199.03 g/mol
Exact mass	197.985
Grade	Reference Standard
HSN code	38229090
InChIKey	BLLMZKROLCVGEC-UHFFFAOYSA-N
SMILES	CCOC(=O)C(C(=O)C)(Cl)Cl
PubChem CID	80217

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	0 / 3
TPSA	43.4 Å²
Synonyms	Ethyl-2,2-Dichloro Acetoacetate, Ethyl 2,2-dichloroacetoacetate, Butanoic acid, 2,2-dichloro-3-oxo-, ethyl ester, Acetoacetic acid, 2,2-dichloro-, ethyl ester, Ethyl .alpha.,.alpha.-dichloroacetoacetate, Ethyl alpha,alpha-dichloroacetoacetate, 2,2-dichloro-a, Butanoic acid,2,2-dichloro-3-oxo-, ethyl ester, 2,2-dichloro-acetoacetic acid ethyl ester

Safety & hazard information (GHS)

Flammable

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H226Flammable liquid and vapor
H227Combustible liquid
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P210, P233, P240, P241, P242, P243, P260, P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P303 + P361 + P353, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P316, P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ethyl 2,2-dichloro-3-oxobutanoate?

The CAS Registry Number of Ethyl 2,2-dichloro-3-oxobutanoate is 6134-66-3. It is also known as Ethyl-2,2-Dichloro Acetoacetate, Ethyl 2,2-dichloroacetoacetate, Butanoic acid, 2,2-dichloro-3-oxo-, ethyl ester.

What is the molecular formula and molecular weight of Ethyl 2,2-dichloro-3-oxobutanoate?

Ethyl 2,2-dichloro-3-oxobutanoate has the molecular formula C6H8Cl2O3 and a molecular weight of 199.03 g/mol. Its IUPAC name is ethyl 2,2-dichloro-3-oxobutanoate.

What is Ethyl 2,2-dichloro-3-oxobutanoate used for?

Ethyl 2,2-dichloro-3-oxobutanoate is supplied as a characterised reference material related to Febuxostat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ethyl 2,2-dichloro-3-oxobutanoate can I order?

We supply Ethyl 2,2-dichloro-3-oxobutanoate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ethyl 2,2-dichloro-3-oxobutanoate?

Yes. Every lot of Ethyl 2,2-dichloro-3-oxobutanoate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ethyl 2,2-dichloro-3-oxobutanoate be shipped internationally?

Yes. Ethyl 2,2-dichloro-3-oxobutanoate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.