Ethyl benzo[b][1,4]dioxine-2-carboxylate

Name: Ethyl benzo[b][1,4]dioxine-2-carboxylate
Brand: Vaqora Chemicals
SKU: VQ-048089

About Ethyl benzo[b][1,4]dioxine-2-carboxylate

Ethyl benzo[b][1,4]dioxine-2-carboxylate is an impurity of Doxazosin carrying the CAS registry number 63881-51-6. Its molecular formula is C11H10O4 and its molecular weight is 206.19 g/mol. Systematically, it is named ethyl 1,4-benzodioxine-3-carboxylate. Common synonyms include Ethyl 1,4-benzodioxin-2-carboxylate and ethyl 1,4-benzodioxine-2-carboxylate.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Doxazosin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Doxazosin

View every impurity, metabolite and intermediate we list for Doxazosin.

Doxazosin impurities

Specifications & identifiers

Chemical identifiers
Product name	Ethyl benzo[b][1,4]dioxine-2-carboxylate
Catalogue No.	VQ-048089
CAS Number	63881-51-6
IUPAC name	ethyl 1,4-benzodioxine-3-carboxylate
Molecular formula	C₁₁H₁₀O₄
Molecular weight	206.19 g/mol
Exact mass	206.0579
Grade	Reference Standard
HSN code	38229090
InChIKey	HYAIFRZTFJBMMC-UHFFFAOYSA-N
SMILES	CCOC(=O)C1=COC2=CC=CC=C2O1
PubChem CID	10987416

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	0 / 4
TPSA	44.8 Å²
Synonyms	Ethyl 1,4-benzodioxin-2-carboxylate, 1,4-Benzodioxin-2-carboxylic acid, ethyl ester, ethyl 1,4-benzodioxine-2-carboxylate, Benzo[1,4]dioxine-2-carboxylic acid ethyl ester, [1,4]benzodioxine-2-carboxylic acid ethyl ester

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H317May cause an allergic skin reaction
H319Causes serious eye irritation

Precautionary statements: P261, P264 + P265, P272, P280, P302 + P352, P305 + P351 + P338, P321, P333 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ethyl benzo[b][1,4]dioxine-2-carboxylate?

The CAS Registry Number of Ethyl benzo[b][1,4]dioxine-2-carboxylate is 63881-51-6. It is also known as Ethyl 1,4-benzodioxin-2-carboxylate, 1,4-Benzodioxin-2-carboxylic acid, ethyl ester, ethyl 1,4-benzodioxine-2-carboxylate.

What is the molecular formula and molecular weight of Ethyl benzo[b][1,4]dioxine-2-carboxylate?

Ethyl benzo[b][1,4]dioxine-2-carboxylate has the molecular formula C11H10O4 and a molecular weight of 206.19 g/mol. Its IUPAC name is ethyl 1,4-benzodioxine-3-carboxylate.

What is Ethyl benzo[b][1,4]dioxine-2-carboxylate used for?

Ethyl benzo[b][1,4]dioxine-2-carboxylate is supplied as a characterised reference material related to Doxazosin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ethyl benzo[b][1,4]dioxine-2-carboxylate can I order?

We supply Ethyl benzo[b][1,4]dioxine-2-carboxylate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ethyl benzo[b][1,4]dioxine-2-carboxylate?

Yes. Every lot of Ethyl benzo[b][1,4]dioxine-2-carboxylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ethyl benzo[b][1,4]dioxine-2-carboxylate be shipped internationally?

Yes. Ethyl benzo[b][1,4]dioxine-2-carboxylate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.