Ethyl Difluoroacetate

Name: Ethyl Difluoroacetate
Brand: Vaqora Chemicals
SKU: VQ-049882

About Ethyl Difluoroacetate

Ethyl Difluoroacetate (CAS 454-31-9) is a process intermediate or related compound of Deracoxib offered by Vaqora Chemicals. Formula C4H6F2O2, molecular weight 124.09 g/mol. Systematically, it is named ethyl 2,2-difluoroacetate. It is also known as Acetic acid, difluoro-, ethyl ester or Acetic acid, 2,2-difluoro-, ethyl ester.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Deracoxib, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Ethyl Difluoroacetate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Deracoxib

View every impurity, metabolite and intermediate we list for Deracoxib.

Deracoxib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ethyl Difluoroacetate
Catalogue No.	VQ-049882
CAS Number	454-31-9
IUPAC name	ethyl 2,2-difluoroacetate
Molecular formula	C₄H₆F₂O₂
Molecular weight	124.09 g/mol
Exact mass	124.0336
InChIKey	GZKHDVAKKLTJPO-UHFFFAOYSA-N
SMILES	CCOC(=O)C(F)F
PubChem CID	9961

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	0 / 4
TPSA	26.3 Å²
Synonyms	Acetic acid, difluoro-, ethyl ester, Acetic acid, 2,2-difluoro-, ethyl ester, Difluoroacetic Acid Ethyl Ester, difluoro-acetic acid ethyl ester, Ethyl difluoroacetic, ethyl difluoroacetic acid, ethyl difluroacetate, 2,2-Difluoroacetic acid ethyl ester, Difluoro-aceticaciethylester

Safety & hazard information (GHS)

Flammable

Corrosive

Environmental hazard

Signal word: Danger

Hazard statements

H225Highly flammable liquid and vapor
H226Flammable liquid and vapor
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P210, P233, P240, P241, P242, P243, P260, P264, P264 + P265, P273, P280, P301 + P330 + P331, P302 + P361 + P354, P303 + P361 + P353, P304 + P340, P305 + P354 + P338, P316, P317, P321, P363, P370 + P378, P391, P403 + P235, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ethyl Difluoroacetate?

The CAS Registry Number of Ethyl Difluoroacetate is 454-31-9. It is also known as Acetic acid, difluoro-, ethyl ester, Acetic acid, 2,2-difluoro-, ethyl ester, Difluoroacetic Acid Ethyl Ester.

What is the molecular formula and molecular weight of Ethyl Difluoroacetate?

Ethyl Difluoroacetate has the molecular formula C4H6F2O2 and a molecular weight of 124.09 g/mol. Its IUPAC name is ethyl 2,2-difluoroacetate.

What is Ethyl Difluoroacetate used for?

Ethyl Difluoroacetate is supplied as a characterised reference material related to Deracoxib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ethyl Difluoroacetate can I order?

We supply Ethyl Difluoroacetate, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ethyl Difluoroacetate?

Yes. Every lot of Ethyl Difluoroacetate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ethyl Difluoroacetate be shipped internationally?

Yes. Ethyl Difluoroacetate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.