Evobrutinib

Name: Evobrutinib
Brand: Vaqora Chemicals
SKU: VQ-031120

About Evobrutinib

Vaqora Chemicals supplies Evobrutinib, a high-purity reference standard of Evobrutinib registered under CAS number 1415823-73-2. With the molecular formula C25H27N5O2, it has a molar mass of 429.5 g/mol. Its systematic (IUPAC) name is 1-[4-[[[6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl]amino]methyl]piperidin-1-yl]prop-2-en-1-one. It is also known as EX-A2691 or Evobrutinib (M-2951).

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Evobrutinib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Evobrutinib in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Evobrutinib

View every impurity, metabolite and intermediate we list for Evobrutinib.

Evobrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Evobrutinib
Catalogue No.	VQ-031120
CAS Number	1415823-73-2
IUPAC name	1-[4-[[[6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl]amino]methyl]piperidin-1-yl]prop-2-en-1-one
Molecular formula	C₂₅H₂₇N₅O₂
Molecular weight	429.5 g/mol
Exact mass	429.2165
Grade	Reference Standard
HSN code	38229090
InChIKey	QUIWHXQETADMGN-UHFFFAOYSA-N
SMILES	C=CC(=O)N1CCC(CC1)CNC2=NC=NC(=C2C3=CC=C(C=C3)OC4=CC=CC=C4)N
PubChem CID	71479709

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	2 / 6
TPSA	93.4 Å²
Synonyms	1-(4-((6-Amino-5-(4-phenoxy-phenyl)-pyrimidin-4-ylamino)-methyl)-piperidin-1-yl)-propenone, EX-A2691, Evobrutinib (M-2951), US9580449, Example A39, US9580449, Example A250, N-[(1-acryloylpiperidin-4-yl)methyl]-5-(4-phenoxyphenyl)pyrimidine-4,6-diamine

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Evobrutinib?

The CAS Registry Number of Evobrutinib is 1415823-73-2. It is also known as 1-(4-((6-Amino-5-(4-phenoxy-phenyl)-pyrimidin-4-ylamino)-methyl)-piperidin-1-yl)-propenone, EX-A2691, Evobrutinib (M-2951).

What is the molecular formula and molecular weight of Evobrutinib?

Evobrutinib has the molecular formula C25H27N5O2 and a molecular weight of 429.5 g/mol. Its IUPAC name is 1-[4-[[[6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl]amino]methyl]piperidin-1-yl]prop-2-en-1-one.

What is Evobrutinib used for?

Evobrutinib is supplied as a characterised reference material related to Evobrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Evobrutinib can I order?

We supply Evobrutinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Evobrutinib?

Yes. Every lot of Evobrutinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Evobrutinib be shipped internationally?

Yes. Evobrutinib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.