Ezetimibe ring open impurity

Name: Ezetimibe ring open impurity
Brand: Vaqora Chemicals
SKU: VQ-022622

About Ezetimibe ring open impurity

Ezetimibe ring open impurity is a metabolite or degradation product of Ezetimibe carrying the CAS registry number 1197811-72-5. Formula C24H23F2NO3, molecular weight 411.4 g/mol. Its systematic (IUPAC) name is (2R,5S)-N,5-bis(4-fluorophenyl)-5-hydroxy-2-[(4-hydroxyphenyl)methyl]pentanamide. It is also known as Ring opened ezetimibe impurity or Ezetimibe Open-Ring Amide Impurity.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Ezetimibe, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Ezetimibe ring open impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Ezetimibe

View every impurity, metabolite and intermediate we list for Ezetimibe.

Ezetimibe impurities

Specifications & identifiers

Chemical identifiers
Product name	Ezetimibe ring open impurity
Catalogue No.	VQ-022622
CAS Number	1197811-72-5
IUPAC name	(2R,5S)-N,5-bis(4-fluorophenyl)-5-hydroxy-2-[(4-hydroxyphenyl)methyl]pentanamide
Molecular formula	C₂₄H₂₃F₂NO₃
Molecular weight	411.4 g/mol
Exact mass	411.1646
Grade	Reference Standard
HSN code	38229090
InChIKey	CJMGACWDXHCPAC-JPYJTQIMSA-N
SMILES	C1=CC(=CC=C1C[C@@H](CC[C@@H](C2=CC=C(C=C2)F)O)C(=O)NC3=CC=C(C=C3)F)O
PubChem CID	58284448

Physical properties
Physical form	Solid
LogP (XLogP3)	4.4
H-bond donors / acceptors	3 / 5
TPSA	69.6 Å²
Synonyms	Ring opened ezetimibe impurity, Ezetimibe Open-Ring Amide Impurity, 2-(4-Hydroxybenzyl)-N,5-bis-(4-fluorophenyl)-5-hydroxypentanamide, (2R,5S)-N,5-bis(4-fluorophenyl)-5-hydroxy-2-(4-hydroxybenzyl)pentanamide, C24 H23 F2 N O3, N,5-Bis(4-fluorophenyl)-5-hydroxy-2-(4-hydroxybenzyl)pentanamide, Ezetimibe Impurity 13(Open Ring Impurity)

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ezetimibe ring open impurity?

The CAS Registry Number of Ezetimibe ring open impurity is 1197811-72-5. It is also known as Ring opened ezetimibe impurity, Ezetimibe Open-Ring Amide Impurity, 2-(4-Hydroxybenzyl)-N,5-bis-(4-fluorophenyl)-5-hydroxypentanamide.

What is the molecular formula and molecular weight of Ezetimibe ring open impurity?

Ezetimibe ring open impurity has the molecular formula C24H23F2NO3 and a molecular weight of 411.4 g/mol. Its IUPAC name is (2R,5S)-N,5-bis(4-fluorophenyl)-5-hydroxy-2-[(4-hydroxyphenyl)methyl]pentanamide.

What is Ezetimibe ring open impurity used for?

Ezetimibe ring open impurity is supplied as a characterised reference material related to Ezetimibe. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ezetimibe ring open impurity can I order?

We supply Ezetimibe ring open impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ezetimibe ring open impurity?

Yes. Every lot of Ezetimibe ring open impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ezetimibe ring open impurity be shipped internationally?

Yes. We export Ezetimibe ring open impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.