Fazarabine

Name: Fazarabine
Brand: Vaqora Chemicals
SKU: VQ-035885

About Fazarabine

Listed under CAS 65886-71-7, Fazarabine is an impurity of Azacitidine available from Vaqora Chemicals. With the molecular formula C8H12N4O5, it has a molar mass of 244.2 g/mol. Systematically, it is named 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one. Alternative names: Ara-AC and 5-Azacytosine arabinoside.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Azacitidine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Fazarabine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Azacitidine

View every impurity, metabolite and intermediate we list for Azacitidine.

Azacitidine impurities

Specifications & identifiers

Chemical identifiers
Product name	Fazarabine
Catalogue No.	VQ-035885
CAS Number	65886-71-7
IUPAC name	4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
Molecular formula	C₈H₁₂N₄O₅
Molecular weight	244.2 g/mol
Exact mass	244.0808
Grade	Reference Standard
HSN code	38229090
InChIKey	NMUSYJAQQFHJEW-ARQDHWQXSA-N
SMILES	C1=NC(=NC(=O)N1[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O)N
PubChem CID	47751

Physical properties
Physical form	Solid
LogP (XLogP3)	-2.2
H-bond donors / acceptors	4 / 5
TPSA	141 Å²
Synonyms	Ara-AC, 5-Azacytosine arabinoside, Kymarabine, 1-beta-D-Arabinofuranosyl-5-azacytosine, 1-beta-D-arabinosyl-5-azacytosine, 1,3,5-Triazin-2(1H)-one, 4-amino-1-beta-D-arabinofuranosyl-, 4-Amino-1-beta-D-arabinofuranosyl-1,3,5-triazin-2(1H)-one, arabinofuranosyl-5-azacytosine, ara-5-azacytosine, ara-5-aza-Cyd, arabinosyl-5-azacytosine, 4-Amino-1-beta-D-arabinofuranosyl-s-triazin-2(1H)-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Fazarabine?

The CAS Registry Number of Fazarabine is 65886-71-7. It is also known as Ara-AC, 5-Azacytosine arabinoside, Kymarabine.

What is the molecular formula and molecular weight of Fazarabine?

Fazarabine has the molecular formula C8H12N4O5 and a molecular weight of 244.2 g/mol. Its IUPAC name is 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one.

What is Fazarabine used for?

Fazarabine is supplied as a characterised reference material related to Azacitidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Fazarabine can I order?

We supply Fazarabine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Fazarabine?

Yes. Every lot of Fazarabine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Fazarabine be shipped internationally?

Yes. Fazarabine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.