Fludrocortisone

Name: Fludrocortisone
Brand: Vaqora Chemicals
SKU: VQ-025817

About Fludrocortisone

Vaqora Chemicals supplies Fludrocortisone, a high-purity reference standard of Fludrocortisone registered under CAS number 127-31-1. Formula C21H29FO5, molecular weight 380.4 g/mol. It is also known as Astonin-H or Alflorone.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Fludrocortisone, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Fludrocortisone is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Fludrocortisone

View every impurity, metabolite and intermediate we list for Fludrocortisone.

Fludrocortisone impurities

Specifications & identifiers

Chemical identifiers
Product name	Fludrocortisone
Catalogue No.	VQ-025817
CAS Number	127-31-1
IUPAC name	(8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
Molecular formula	C₂₁H₂₉FO₅
Molecular weight	380.4 g/mol
Exact mass	380.1999
Grade	Reference Standard
HSN code	38229090
InChIKey	AAXVEMMRQDVLJB-BULBTXNYSA-N
SMILES	C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@]2([C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O)F
PubChem CID	31378

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	3 / 6
TPSA	94.8 Å²
Synonyms	Astonin-H, Alflorone, Fluohydrisone, Fluorocortisol, Fluorocortisone, 9alpha-Fluorocortisol, Fluohydrocortisone, Fludrocortone, Fludrone, F-Cortef, 9-Fluorocortisol, F-COL

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Fludrocortisone?

The CAS Registry Number of Fludrocortisone is 127-31-1. It is also known as Astonin-H, Alflorone, Fluohydrisone.

What is the molecular formula and molecular weight of Fludrocortisone?

Fludrocortisone has the molecular formula C21H29FO5 and a molecular weight of 380.4 g/mol. Its IUPAC name is (8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one.

What is Fludrocortisone used for?

Fludrocortisone is supplied as a characterised reference material related to Fludrocortisone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Fludrocortisone can I order?

We supply Fludrocortisone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Fludrocortisone?

Yes. Every lot of Fludrocortisone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Fludrocortisone be shipped internationally?

Yes. Fludrocortisone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.