Fluticasone 17-beta-Carboxylic Acid

Name: Fluticasone 17-beta-Carboxylic Acid
Brand: Vaqora Chemicals
SKU: VQ-022698

About Fluticasone 17-beta-Carboxylic Acid

Fluticasone 17-beta-Carboxylic Acid (CAS 28416-82-2) is an impurity of Fluticasone offered by Vaqora Chemicals. With the molecular formula C21H26F2O5, it has a molar mass of 396.4 g/mol. Alternative names: Fluticasone 17β-Carboxylic Acid and Flumethasone Acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 5 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Fluticasone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Fluticasone 17-beta-Carboxylic Acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Fluticasone

View every impurity, metabolite and intermediate we list for Fluticasone.

Fluticasone impurities

Specifications & identifiers

Chemical identifiers
Product name	Fluticasone 17-beta-Carboxylic Acid
Catalogue No.	VQ-022698
CAS Number	28416-82-2
IUPAC name	(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carboxylic acid
Molecular formula	C₂₁H₂₆F₂O₅
Molecular weight	396.4 g/mol
Exact mass	396.1748
Grade	Reference Standard
HSN code	38229090
InChIKey	QSVBUQTYFQFEHC-IDIDPBNYSA-N
SMILES	C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)O)O)C)O)F)C)F
PubChem CID	9822089

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	3 / 7
TPSA	94.8 Å²
Synonyms	Fluticasone 17β-Carboxylic Acid, Flumethasone Acid, Fluticasone 17, A-Carboxylic Acid, Fluticasone Carboxylic Acid, Fluticasone 17b-Carboxylic Acid, Discontinued see F599490, 6a,9a-Difluoro-11b,17a-dihydroxy -16a-methylpregna-3-oxo-1,4-diene-17b-carboxylic acid

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H341Suspected of causing genetic defects
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P270, P273, P280, P301 + P317, P318, P319, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Fluticasone 17-beta-Carboxylic Acid?

The CAS Registry Number of Fluticasone 17-beta-Carboxylic Acid is 28416-82-2. It is also known as Fluticasone 17β-Carboxylic Acid, Flumethasone Acid, Fluticasone 17.

What is the molecular formula and molecular weight of Fluticasone 17-beta-Carboxylic Acid?

Fluticasone 17-beta-Carboxylic Acid has the molecular formula C21H26F2O5 and a molecular weight of 396.4 g/mol.

What is Fluticasone 17-beta-Carboxylic Acid used for?

Fluticasone 17-beta-Carboxylic Acid is supplied as a characterised reference material related to Fluticasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Fluticasone 17-beta-Carboxylic Acid can I order?

We supply Fluticasone 17-beta-Carboxylic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Fluticasone 17-beta-Carboxylic Acid?

Yes. Every lot of Fluticasone 17-beta-Carboxylic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Fluticasone 17-beta-Carboxylic Acid be shipped internationally?

Yes. Fluticasone 17-beta-Carboxylic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.