Fmoc-O-tert-butyl-D-trans-4-hydroxyproline

Name: Fmoc-O-tert-butyl-D-trans-4-hydroxyproline
Brand: Vaqora Chemicals
SKU: VQ-040184

About Fmoc-O-tert-butyl-D-trans-4-hydroxyproline

Vaqora Chemicals supplies Fmoc-O-tert-butyl-D-trans-4-hydroxyproline, a metabolite / degradant standard registered under CAS number 268729-12-0. Its molecular formula is C24H27NO5 and its molecular weight is 409.5 g/mol. Systematically, it is named (2R,4S)-1-(9H-fluoren-9-ylmethoxycarbonyl)-4-[(2-methylpropan-2-yl)oxy]pyrrolidine-2-carboxylic acid. It is also known as Fmoc-D-Hyp(tBu)-OH or Fmoc-O-tert-butyl-D-4-hydroxyproline.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Fmoc-O-tert-butyl-D-trans-4-hydroxyproline is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Specifications & identifiers

Chemical identifiers
Product name	Fmoc-O-tert-butyl-D-trans-4-hydroxyproline
Catalogue No.	VQ-040184
CAS Number	268729-12-0
IUPAC name	(2R,4S)-1-(9H-fluoren-9-ylmethoxycarbonyl)-4-[(2-methylpropan-2-yl)oxy]pyrrolidine-2-carboxylic acid
Molecular formula	C₂₄H₂₇NO₅
Molecular weight	409.5 g/mol
Exact mass	409.1889
Grade	Reference Standard
HSN code	38229090
InChIKey	WPBXBYOKQUEIDW-YCRPNKLZSA-N
SMILES	CC(C)(C)O[C@H]1C[C@@H](N(C1)C(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)C(=O)O
PubChem CID	978348

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	1 / 5
TPSA	76.1 Å²
Synonyms	Fmoc-D-Hyp(tBu)-OH, Fmoc-O-tert-butyl-D-4-hydroxyproline, Fmoc-o-t-Butyl-D-trans-4-hydroxyproline, Fmoc-trans-D-Hyp(tBu)-OH, (4S)-4-tert-Butoxy-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-D-proline, (2R,4S)-4-tert-butoxy-1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidine-2-carboxylic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Fmoc-O-tert-butyl-D-trans-4-hydroxyproline?

The CAS Registry Number of Fmoc-O-tert-butyl-D-trans-4-hydroxyproline is 268729-12-0. It is also known as Fmoc-D-Hyp(tBu)-OH, Fmoc-O-tert-butyl-D-4-hydroxyproline, Fmoc-o-t-Butyl-D-trans-4-hydroxyproline.

What is the molecular formula and molecular weight of Fmoc-O-tert-butyl-D-trans-4-hydroxyproline?

Fmoc-O-tert-butyl-D-trans-4-hydroxyproline has the molecular formula C24H27NO5 and a molecular weight of 409.5 g/mol. Its IUPAC name is (2R,4S)-1-(9H-fluoren-9-ylmethoxycarbonyl)-4-[(2-methylpropan-2-yl)oxy]pyrrolidine-2-carboxylic acid.

Which grade and pack sizes of Fmoc-O-tert-butyl-D-trans-4-hydroxyproline can I order?

We supply Fmoc-O-tert-butyl-D-trans-4-hydroxyproline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Fmoc-O-tert-butyl-D-trans-4-hydroxyproline?

Yes. Every lot of Fmoc-O-tert-butyl-D-trans-4-hydroxyproline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Fmoc-O-tert-butyl-D-trans-4-hydroxyproline be shipped internationally?

Yes. We export Fmoc-O-tert-butyl-D-trans-4-hydroxyproline worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.