Fosaprepitant Dimeglumine

Name: Fosaprepitant Dimeglumine
Brand: Vaqora Chemicals
SKU: VQ-013443

About Fosaprepitant Dimeglumine

Vaqora Chemicals supplies Fosaprepitant Dimeglumine, a process intermediate or related compound of Fosaprepitant registered under CAS number 265121-04-8. Formula C37H56F7N6O16P, molecular weight 1004.8 g/mol. It is also known as Fosaprepitant di(N-methylglucamine) or Fosaprepitant meglumine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Fosaprepitant, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Fosaprepitant Dimeglumine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Fosaprepitant

View every impurity, metabolite and intermediate we list for Fosaprepitant.

Fosaprepitant impurities

Specifications & identifiers

Chemical identifiers
Product name	Fosaprepitant Dimeglumine
Catalogue No.	VQ-013443
CAS Number	265121-04-8
IUPAC name	[3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid;bis((2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol)
Molecular formula	C₃₇H₅₆F₇N₆O₁₆P
Molecular weight	1004.8 g/mol
Exact mass	1004.3379
Grade	Reference Standard
HSN code	2933
InChIKey	VRQHBYGYXDWZDL-OOZCZQCLSA-N
SMILES	C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)CC3=NN(C(=O)N3)P(=O)(O)O)C4=CC=C(C=C4)F.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
PubChem CID	135564864

Physical properties
Physical form	Solid
H-bond donors / acceptors	15 / 27
TPSA	350 Å²
Synonyms	Fosaprepitant di(N-methylglucamine), Fosaprepitant meglumine, Emend for injection, Fosaprepitant dimeglumine salt, Fosaprepitant (dimeglumine), Fosaprepitant meglumine (JAN), Fosaprepitant dimeglumine (USAN), Proemend (TN), Fosaprepitant dimeglumine?, Fosaprepitant (as dimeglumine), EX-A1255, Fosaprepitant (dimeglumine) (Standard)

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H373May causes damage to organs through prolonged or repeated exposure
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P260, P264, P264 + P265, P270, P273, P280, P301 + P317, P302 + P352, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Fosaprepitant Dimeglumine?

The CAS Registry Number of Fosaprepitant Dimeglumine is 265121-04-8. It is also known as Fosaprepitant di(N-methylglucamine), Fosaprepitant meglumine, Emend for injection.

What is the molecular formula and molecular weight of Fosaprepitant Dimeglumine?

Fosaprepitant Dimeglumine has the molecular formula C37H56F7N6O16P and a molecular weight of 1004.8 g/mol.

What is Fosaprepitant Dimeglumine used for?

Fosaprepitant Dimeglumine is supplied as a characterised reference material related to Fosaprepitant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Fosaprepitant Dimeglumine can I order?

We supply Fosaprepitant Dimeglumine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Fosaprepitant Dimeglumine?

Yes. Every lot of Fosaprepitant Dimeglumine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Fosaprepitant Dimeglumine be shipped internationally?

Yes. Fosaprepitant Dimeglumine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.