Fruquintinib

Name: Fruquintinib
Brand: Vaqora Chemicals
SKU: VQ-025929

About Fruquintinib

Vaqora Chemicals supplies Fruquintinib, a high-purity reference standard of Fruquintinib registered under CAS number 1194506-26-7. Its molecular formula is C21H19N3O5 and its molecular weight is 393.4 g/mol. Systematically, it is named 6-(6,7-dimethoxyquinazolin-4-yl)oxy-N,2-dimethyl-1-benzofuran-3-carboxamide. Alternative names: Fruquintinib (WSM) and HMPL-013.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Fruquintinib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Fruquintinib is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Fruquintinib

View every impurity, metabolite and intermediate we list for Fruquintinib.

Fruquintinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Fruquintinib
Catalogue No.	VQ-025929
CAS Number	1194506-26-7
IUPAC name	6-(6,7-dimethoxyquinazolin-4-yl)oxy-N,2-dimethyl-1-benzofuran-3-carboxamide
Molecular formula	C₂₁H₁₉N₃O₅
Molecular weight	393.4 g/mol
Exact mass	393.1325
Grade	Reference Standard
HSN code	38229090
InChIKey	BALLNEJQLSTPIO-UHFFFAOYSA-N
SMILES	CC1=C(C2=C(O1)C=C(C=C2)OC3=NC=NC4=CC(=C(C=C43)OC)OC)C(=O)NC
PubChem CID	44480399

Physical properties
Physical form	Solid
LogP (XLogP3)	3.4
H-bond donors / acceptors	1 / 7
TPSA	95.7 Å²
Synonyms	Fruquintinib (WSM), HMPL-013, Elunate, 6-[(6,7-dimethoxyquinazolin-4-yl)oxy]-N,2-dimethyl-1-benzofuran-3-carboxamide, 6-(6,7-dimethoxyquinazolin-4-yloxy)-N,2-dimethylbenzofuran-3-carboxamide, 3-Benzofurancarboxamide, 6-((6,7-dimethoxy-4-quinazolinyl)oxy)-N,2-dimethyl-, 3-Benzofurancarboxamide, 6-[(6,7-dimethoxy-4-quinazolinyl)oxy]-N,2-dimethyl-, 6-((6,7-dimethoxyquinazolin-4-yl)oxy)-N,2-dimethyl-1-benzofuran-3-carboxamide, VEGFR-1/2/3 Inhibitor HMPL-013, 6-((6,7-dimethoxyquinazolin-4-yl)oxy)-N,2-dimethylbenzofuran-3-carboxamide, 6-[(6,7-Dimethoxy-4-quinazolinyl)oxy]-N,2-dimethyl-3-benzofurancarboxamide, Fruquintinib (HMPL-013)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Fruquintinib?

The CAS Registry Number of Fruquintinib is 1194506-26-7. It is also known as Fruquintinib (WSM), HMPL-013, Elunate.

What is the molecular formula and molecular weight of Fruquintinib?

Fruquintinib has the molecular formula C21H19N3O5 and a molecular weight of 393.4 g/mol. Its IUPAC name is 6-(6,7-dimethoxyquinazolin-4-yl)oxy-N,2-dimethyl-1-benzofuran-3-carboxamide.

What is Fruquintinib used for?

Fruquintinib is supplied as a characterised reference material related to Fruquintinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Fruquintinib can I order?

We supply Fruquintinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Fruquintinib?

Yes. Every lot of Fruquintinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Fruquintinib be shipped internationally?

Yes. Fruquintinib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.