Gefitinib

Name: Gefitinib
Brand: Vaqora Chemicals
SKU: VQ-019529

About Gefitinib

Vaqora Chemicals supplies Gefitinib, a diazine derivative registered under CAS number 184475-35-2. The compound has the formula C22H24ClFN4O3, corresponding to a molecular weight of 446.9 g/mol. Its systematic (IUPAC) name is N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine. Alternative names: gefitinib (zd1839).

Store in a tightly closed container in a cool, dry and well-ventilated place. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Key uses span cell and microbial culture and organic synthesis. It is used across pharmaceutical manufacturing, academic and industrial research and diagnostics and biotechnology.

Standard pack sizes are 1 g and 5 g, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. A Safety Data Sheet (SDS) and technical specifications are available on request. Larger quantities and custom packaging are available. Request a quote for pricing and lead time.

Typical applications

Cell & microbial culture
Organic synthesis

Industries

Specifications & identifiers

Chemical identifiers
Product name	Gefitinib
Catalogue No.	VQ-019529
CAS Number	184475-35-2
IUPAC name	N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
Molecular formula	C₂₂H₂₄ClFN₄O₃
Molecular weight	446.9 g/mol
Exact mass	446.1521
HSN code	2933
InChIKey	XGALLCVXEZPNRQ-UHFFFAOYSA-N
SMILES	COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4
PubChem CID	123631

Physical properties
Physical form	Other
LogP (XLogP3)	4.1
H-bond donors / acceptors	1 / 8
TPSA	68.7 Å²
Synonyms	N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine, 4-(3'-Chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline, 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine, 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-, N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-(morpholin-4-yl)propoxy)quinazolin-4-amine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamide, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholin) propoxy)-4-quinazolinamine, N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine, gefitinib (zd1839)

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P264 + P265, P270, P273, P280, P301 + P317, P302 + P352, P305 + P354 + P338, P317, P318, P319, P321, P330, P332 + P317, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 184475-35-2

Cell Culture

Gefitinib, cell culture tested

CAS: 184475-35-2
Formula: C₂₂H₂₄ClFN₄O₃
MW: 446.9 g/mol

VQ-020304

Frequently asked questions

What is the CAS number of Gefitinib?

The CAS Registry Number of Gefitinib is 184475-35-2. It is also known as N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine, 4-(3'-Chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline.

What is the molecular formula and molecular weight of Gefitinib?

Gefitinib has the molecular formula C22H24ClFN4O3 and a molecular weight of 446.9 g/mol. Its IUPAC name is N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine.

Which grade and pack sizes of Gefitinib can I order?

We supply Gefitinib, in 1 g, 5 g packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Gefitinib?

Yes. Every lot of Gefitinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Gefitinib be shipped internationally?

Yes. Gefitinib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.