Hydrocortisone hemisuccinate hydrate

Name: Hydrocortisone hemisuccinate hydrate
Brand: Vaqora Chemicals
SKU: VQ-031083

About Hydrocortisone hemisuccinate hydrate

Listed under CAS 83784-20-7, Hydrocortisone hemisuccinate hydrate is a high-purity reference standard of Hydrocortisone available from Vaqora Chemicals. The compound has the formula C25H36O9, corresponding to a molecular weight of 480.5 g/mol. It is also known as hydrocortisone hemisuccinate or cortisol-21-(hydrogen succinate).

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 6 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Hydrocortisone, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Hydrocortisone hemisuccinate hydrate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Hydrocortisone

View every impurity, metabolite and intermediate we list for Hydrocortisone.

Hydrocortisone impurities

Specifications & identifiers

Chemical identifiers
Product name	Hydrocortisone hemisuccinate hydrate
Catalogue No.	VQ-031083
CAS Number	83784-20-7
IUPAC name	4-[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethoxy]-4-oxobutanoic acid;hydrate
Molecular formula	C₂₅H₃₆O₉
Molecular weight	480.5 g/mol
Exact mass	480.2359
Grade	Reference Standard
HSN code	38229090
InChIKey	AFLWPAGYTPJSEY-CODXZCKSSA-N
SMILES	C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)COC(=O)CCC(=O)O)O)C)O.O
PubChem CID	219121

Physical properties
Physical form	Solid
H-bond donors / acceptors	4 / 9
TPSA	139 Å²
Synonyms	hydrocortisone hemisuccinate, cortisol-21-(hydrogen succinate), Cortisol hemisuccinate, Cortisol 21-(hydrogen succinate) monohydrate, Hydrocortisone-21 hemisuccinate monohydrate, 21-(3-Carboxypropanoyl)-11beta,17-dihydroxypregn-4-ene-3,20-dione monohydrate, 4-[(11beta,17-Dihydroxy-3,20-dioxopregn-4-en-21-yl)oxy]-4-oxobutanoic acid--water (1/1)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P318, P321, P330, P332 + P317, P337 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hydrocortisone hemisuccinate hydrate?

The CAS Registry Number of Hydrocortisone hemisuccinate hydrate is 83784-20-7. It is also known as hydrocortisone hemisuccinate, cortisol-21-(hydrogen succinate), Cortisol hemisuccinate.

What is the molecular formula and molecular weight of Hydrocortisone hemisuccinate hydrate?

Hydrocortisone hemisuccinate hydrate has the molecular formula C25H36O9 and a molecular weight of 480.5 g/mol.

What is Hydrocortisone hemisuccinate hydrate used for?

Hydrocortisone hemisuccinate hydrate is supplied as a characterised reference material related to Hydrocortisone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hydrocortisone hemisuccinate hydrate can I order?

We supply Hydrocortisone hemisuccinate hydrate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hydrocortisone hemisuccinate hydrate?

Yes. Every lot of Hydrocortisone hemisuccinate hydrate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hydrocortisone hemisuccinate hydrate be shipped internationally?

Yes. Hydrocortisone hemisuccinate hydrate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.