Hydroxizine

Name: Hydroxizine
Brand: Vaqora Chemicals
SKU: VQ-013452

About Hydroxizine

Hydroxizine is a process intermediate or related compound of Cetirizine carrying the CAS registry number 68-88-2. With the molecular formula C21H27ClN2O2, it has a molar mass of 374.9 g/mol. Systematically, it is named 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol. It is also known as (±)-Hydroxyzine or Hydroxyzine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Cetirizine, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Hydroxizine is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Cetirizine

View every impurity, metabolite and intermediate we list for Cetirizine.

Cetirizine impurities

Specifications & identifiers

Chemical identifiers
Product name	Hydroxizine
Catalogue No.	VQ-013452
CAS Number	68-88-2
Other CAS	1244-76-4
IUPAC name	2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol
Molecular formula	C₂₁H₂₇ClN₂O₂
Molecular weight	374.9 g/mol
Exact mass	374.1761
Grade	Reference Standard
HSN code	2933
InChIKey	ZQDWXGKKHFNSQK-UHFFFAOYSA-N
SMILES	C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl
PubChem CID	3658

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	1 / 4
TPSA	35.9 Å²
Synonyms	2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)ethanol, 2-[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]ethanol, (±)-Hydroxyzine, 1-(p-Chlorobenzhydryl)-4-[2-(2-hydroxyethoxy)ethyl]piperazine, Hydroxyzine, Hydroxyzyne, Tran-Q, Tranquizine, Hydroxyzin, Hydroxine, Hydroxycine, Hychotine

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H336May cause drowsiness or dizziness
H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P233, P260, P261, P264, P270, P271, P280, P284, P301 + P317, P304 + P340, P318, P319, P330, P342 + P316, P403, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hydroxizine?

The CAS Registry Number of Hydroxizine is 68-88-2. It is also known as 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)ethanol, 2-[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]ethanol, (±)-Hydroxyzine.

What is the molecular formula and molecular weight of Hydroxizine?

Hydroxizine has the molecular formula C21H27ClN2O2 and a molecular weight of 374.9 g/mol. Its IUPAC name is 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol.

What is Hydroxizine used for?

Hydroxizine is supplied as a characterised reference material related to Cetirizine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hydroxizine can I order?

We supply Hydroxizine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hydroxizine?

Yes. Every lot of Hydroxizine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hydroxizine be shipped internationally?

Yes. Hydroxizine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.