Hydroxy Bupropion

Name: Hydroxy Bupropion
Brand: Vaqora Chemicals
SKU: VQ-024690

About Hydroxy Bupropion

Listed under CAS 357399-43-0, Hydroxy Bupropion is a metabolite or degradation product of Bupropion available from Vaqora Chemicals. The compound has the formula C13H18ClNO2, corresponding to a molecular weight of 255.74 g/mol. Its systematic (IUPAC) name is 2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol. Common synonyms include Hydroxy Bupropion (Bupropion Morpholinol) and Bupropion Morpholinol Racemate.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 6 hazard statements. Review the Safety Data Sheet before use.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Bupropion, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Hydroxy Bupropion is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Bupropion

View every impurity, metabolite and intermediate we list for Bupropion.

Bupropion impurities

Specifications & identifiers

Chemical identifiers
Product name	Hydroxy Bupropion
Catalogue No.	VQ-024690
CAS Number	357399-43-0
IUPAC name	2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
Molecular formula	C₁₃H₁₈ClNO₂
Molecular weight	255.74 g/mol
Exact mass	255.1026
Grade	Reference Standard
HSN code	38229090
InChIKey	RCOBKSKAZMVBHT-UHFFFAOYSA-N
SMILES	CC1C(OCC(N1)(C)C)(C2=CC(=CC=C2)Cl)O
PubChem CID	9837966

Physical properties
Physical form	Solid
LogP (XLogP3)	1.9
H-bond donors / acceptors	2 / 3
TPSA	41.5 Å²
Synonyms	Hydroxy Bupropion (Bupropion Morpholinol), Bupropion Morpholinol Racemate, 2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol, Bupropion morpholinol, 2-Hydroxy-2-(3'-chlorophenyl)-3,5,5-trimethylmorpholine, 2-(3-chlorophenyl)-3,5,5-trimethyl-morpholin-2-ol

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Hydroxy Bupropion?

The CAS Registry Number of Hydroxy Bupropion is 357399-43-0. It is also known as Hydroxy Bupropion (Bupropion Morpholinol), Bupropion Morpholinol Racemate, 2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol.

What is the molecular formula and molecular weight of Hydroxy Bupropion?

Hydroxy Bupropion has the molecular formula C13H18ClNO2 and a molecular weight of 255.74 g/mol. Its IUPAC name is 2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol.

What is Hydroxy Bupropion used for?

Hydroxy Bupropion is supplied as a characterised reference material related to Bupropion. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Hydroxy Bupropion can I order?

We supply Hydroxy Bupropion in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Hydroxy Bupropion?

Yes. Every lot of Hydroxy Bupropion is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Hydroxy Bupropion be shipped internationally?

Yes. Hydroxy Bupropion is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.