Icomethasone

Name: Icomethasone
Brand: Vaqora Chemicals
SKU: VQ-026767

About Icomethasone

Vaqora Chemicals supplies Icomethasone, an impurity of Mometasone Furoate registered under CAS number 4647-20-5. With the molecular formula C22H29ClO5, it has a molar mass of 408.9 g/mol. Alternative names: Icometasone and beclometasone, Alza.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Mometasone Furoate, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Icomethasone in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Mometasone Furoate

View every impurity, metabolite and intermediate we list for Mometasone Furoate.

Mometasone Furoate impurities

Specifications & identifiers

Chemical identifiers
Product name	Icomethasone
Catalogue No.	VQ-026767
CAS Number	4647-20-5
IUPAC name	(8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
Molecular formula	C₂₂H₂₉ClO₅
Molecular weight	408.9 g/mol
Exact mass	408.1704
Grade	Reference Standard
HSN code	38229090
InChIKey	NBMKJKDGKREAPL-CXSFZGCWSA-N
SMILES	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)Cl)C
PubChem CID	11407187

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	3 / 5
TPSA	94.8 Å²
Synonyms	Icometasone, Pregna-1,4-diene-3,20-dione, 9-chloro-11,17,21-trihydroxy-16-methyl-, (11beta,16alpha)-, 9-Chloro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione (Icometasone), beclometasone, Alza, 9-Chloro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Icomethasone?

The CAS Registry Number of Icomethasone is 4647-20-5. It is also known as Icometasone, Pregna-1,4-diene-3,20-dione, 9-chloro-11,17,21-trihydroxy-16-methyl-, (11beta,16alpha)-, 9-Chloro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione (Icometasone).

What is the molecular formula and molecular weight of Icomethasone?

Icomethasone has the molecular formula C22H29ClO5 and a molecular weight of 408.9 g/mol. Its IUPAC name is (8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one.

What is Icomethasone used for?

Icomethasone is supplied as a characterised reference material related to Mometasone Furoate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Icomethasone can I order?

We supply Icomethasone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Icomethasone?

Yes. Every lot of Icomethasone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Icomethasone be shipped internationally?

Yes. We export Icomethasone worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.