Idelalisib

Name: Idelalisib
Brand: Vaqora Chemicals
SKU: VQ-037654

About Idelalisib

Vaqora Chemicals supplies Idelalisib, a stable isotope labelled analogue related to Idelalisib registered under CAS number 870281-82-6. Formula C22H18FN7O, molecular weight 415.4 g/mol. The IUPAC name is 5-fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4-one. Common synonyms include CAL-101 and CAL 101.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 2 hazard statements. Review the Safety Data Sheet before use.

This isotope-labelled compound is used as an internal standard for LC-MS and LC-MS/MS quantitation of Idelalisib and related analytes in bioanalytical, pharmacokinetic and impurity studies. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Idelalisib is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

LC-MS/MS internal standard
Bioanalytical quantitation
Pharmacokinetic studies

Industries

Related to Idelalisib

View every impurity, metabolite and intermediate we list for Idelalisib.

Idelalisib impurities

Specifications & identifiers

Chemical identifiers
Product name	Idelalisib
Catalogue No.	VQ-037654
CAS Number	870281-82-6
IUPAC name	5-fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4-one
Molecular formula	C₂₂H₁₈FN₇O
Molecular weight	415.4 g/mol
Exact mass	415.1557
Grade	Reference Standard
HSN code	38229090
InChIKey	IFSDAJWBUCMOAH-HNNXBMFYSA-N
SMILES	CC[C@@H](C1=NC2=C(C(=CC=C2)F)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5
PubChem CID	11625818

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	2 / 7
TPSA	99.2 Å²
Synonyms	CAL-101, 5-Fluoro-3-phenyl-2-((S)-1-(9H-purin-6-ylamino)-propyl)-3H-quinazolin-4-one, 5-fluoro-3-phenyl-2-[(1S)-1-(3H-purin-6-ylamino)propyl]quinazolin-4(3H)-one, 5-fluoro-3-phenyl-2-[(1S)-1-[(9H-purin-6-yl)amino]propyl]-3,4-dihydroquinazolin-4-one, 5-fluoro-3-phenyl-2-((1S)-1-(7H-purin-6-ylamino)propyl)quinazolin-4-one, 5-fluoro-3-phenyl-2-((1S)-1-((9H-purin-6-yl)amino)propyl)-3,4-dihydroquinazolin-4-one, 5-fluoro-3-phenyl-2-((1S)-1-(3H-purin-6-ylamino)propyl)quinazolin-4(3H)-one, Phosphoinositide-3 Kinase Delta Inhibitor CAL-101, CAL 101, (S)-2-(1-((9H-Purin-6-yl)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one, Idelalisib (CAL-101), CAL-101 (Idelalisib, GS-1101)

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H360May damage fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P264, P270, P280, P318, P319, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Idelalisib?

The CAS Registry Number of Idelalisib is 870281-82-6. It is also known as CAL-101, 5-Fluoro-3-phenyl-2-((S)-1-(9H-purin-6-ylamino)-propyl)-3H-quinazolin-4-one, 5-fluoro-3-phenyl-2-[(1S)-1-(3H-purin-6-ylamino)propyl]quinazolin-4(3H)-one.

What is the molecular formula and molecular weight of Idelalisib?

Idelalisib has the molecular formula C22H18FN7O and a molecular weight of 415.4 g/mol. Its IUPAC name is 5-fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4-one.

What is Idelalisib used for?

Idelalisib is supplied as a characterised reference material related to Idelalisib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Idelalisib can I order?

We supply Idelalisib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Idelalisib?

Yes. Every lot of Idelalisib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Idelalisib be shipped internationally?

Yes. Idelalisib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.