Indirubin

Name: Indirubin
Brand: Vaqora Chemicals
SKU: VQ-040566

About Indirubin

Indirubin (CAS 479-41-4) is an API impurity reference standard offered by Vaqora Chemicals. Formula C16H10N2O2, molecular weight 262.26 g/mol. Systematically, it is named 2-(2-hydroxy-1H-indol-3-yl)indol-3-one. Alternative names: Indigopurpurin and Couroupitine B.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of the parent drug substance to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Specifications & identifiers

Chemical identifiers
Product name	Indirubin
Catalogue No.	VQ-040566
CAS Number	479-41-4
IUPAC name	2-(2-hydroxy-1H-indol-3-yl)indol-3-one
Molecular formula	C₁₆H₁₀N₂O₂
Molecular weight	262.26 g/mol
Exact mass	262.0742
Grade	Reference Standard
HSN code	38229090
InChIKey	JNLNPCNGMHKCKO-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)C(=C(N2)O)C3=NC4=CC=CC=C4C3=O
PubChem CID	10177

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	2 / 3
TPSA	65.5 Å²
Synonyms	Indigopurpurin, 2H-Indol-2-one, 3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-, 2H-Indol-2-one, 3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-(9CI), Couroupitine B, Indigo Red, (Z)-[2,3'-biindolinylidene]-2',3-dione, [2,3'-Biindolinylidene]-2',3-dione, Isoindirubin, (E)-[2,3'-biindolinylidene]-2',3-dione, Isoindirubine, Isoindogotin, 2H-Indol-2-one,3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Indirubin?

The CAS Registry Number of Indirubin is 479-41-4. It is also known as Indigopurpurin, 2H-Indol-2-one, 3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-, 2H-Indol-2-one, 3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-(9CI).

What is the molecular formula and molecular weight of Indirubin?

Indirubin has the molecular formula C16H10N2O2 and a molecular weight of 262.26 g/mol. Its IUPAC name is 2-(2-hydroxy-1H-indol-3-yl)indol-3-one.

Which grade and pack sizes of Indirubin can I order?

We supply Indirubin in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Indirubin?

Yes. Every lot of Indirubin is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Indirubin be shipped internationally?

Yes. Indirubin is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.