Indomethacin Methyl Ester

Name: Indomethacin Methyl Ester
Brand: Vaqora Chemicals
SKU: VQ-022851

About Indomethacin Methyl Ester

Indomethacin Methyl Ester is an impurity of Indomethacin carrying the CAS registry number 1601-18-9. Formula C20H18ClNO4, molecular weight 371.8 g/mol. The IUPAC name is methyl 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetate. Alternative names: Indometacin methylester and Indomethacin derivative, 5.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Indomethacin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Indomethacin Methyl Ester in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Indomethacin

View every impurity, metabolite and intermediate we list for Indomethacin.

Indomethacin impurities

Specifications & identifiers

Chemical identifiers
Product name	Indomethacin Methyl Ester
Catalogue No.	VQ-022851
CAS Number	1601-18-9
IUPAC name	methyl 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetate
Molecular formula	C₂₀H₁₈ClNO₄
Molecular weight	371.8 g/mol
Exact mass	371.0924
Grade	Reference Standard
HSN code	38229090
InChIKey	OKHORWCUMZIORR-UHFFFAOYSA-N
SMILES	CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)OC
PubChem CID	15339

Physical properties
Physical form	Solid
LogP (XLogP3)	4.6
H-bond donors / acceptors	0 / 4
TPSA	57.5 Å²
Synonyms	Methyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate, INDOLE-3-ACETIC ACID, 1-(p-CHLOROBENZOYL)-5-METHOXY-2-METHYL-, METHYL ESTER, Methyl 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate, 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, methyl ester, Indometacin methylester, Indomethacin derivative, 5, Methyl ester of Indomethacin, 1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-3-indoleacetic acid methyl ester, Methyl [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetate, methyl 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Indomethacin Methyl Ester?

The CAS Registry Number of Indomethacin Methyl Ester is 1601-18-9. It is also known as Methyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate, INDOLE-3-ACETIC ACID, 1-(p-CHLOROBENZOYL)-5-METHOXY-2-METHYL-, METHYL ESTER, Methyl 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate.

What is the molecular formula and molecular weight of Indomethacin Methyl Ester?

Indomethacin Methyl Ester has the molecular formula C20H18ClNO4 and a molecular weight of 371.8 g/mol. Its IUPAC name is methyl 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetate.

What is Indomethacin Methyl Ester used for?

Indomethacin Methyl Ester is supplied as a characterised reference material related to Indomethacin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Indomethacin Methyl Ester can I order?

We supply Indomethacin Methyl Ester in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Indomethacin Methyl Ester?

Yes. Every lot of Indomethacin Methyl Ester is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Indomethacin Methyl Ester be shipped internationally?

Yes. We export Indomethacin Methyl Ester worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.