Isoescin IB

Name: Isoescin IB
Brand: Vaqora Chemicals
SKU: VQ-030547

About Isoescin IB

Listed under CAS 219944-46-4, Isoescin IB is an impurity of Escin available from Vaqora Chemicals. With the molecular formula C55H86O24, it has a molar mass of 1131.3 g/mol. Common synonyms include Escin ivb and Aescin D.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Escin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Isoescin IB is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Escin

View every impurity, metabolite and intermediate we list for Escin.

Escin impurities

Specifications & identifiers

Chemical identifiers
Product name	Isoescin IB
Catalogue No.	VQ-030547
CAS Number	219944-46-4
IUPAC name	(2S,3S,4S,5R,6R)-6-[[(3S,4S,4aR,6aR,6bS,8R,8aR,9R,10R,12aS,14aR,14bR)-8a-(acetyloxymethyl)-8,9-dihydroxy-4-(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-[(Z)-2-methylbut-2-enoyl]oxy-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-4-hydroxy-3,5-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]oxane-2-carboxylic acid
Molecular formula	C₅₅H₈₆O₂₄
Molecular weight	1131.3 g/mol
Exact mass	1130.5509
Grade	Reference Standard
HSN code	38229090
InChIKey	YOSIWGSGLDDTHJ-OXPBSUTMSA-N
PubChem CID	6476033

Physical properties
Physical form	Solid
LogP (XLogP3)	0.1
H-bond donors / acceptors	13 / 24
TPSA	388 Å²
Synonyms	Escin ivb, Aescin D, Isoescin ib (constituent of horse chestnut), Isoescin ib (constituent of horse chestnut) [DSC], isoescine Ib

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302+H332Harmful if swallowed or if inhaled
H302Harmful if swallowed
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P301 + P317, P304 + P340, P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Isoescin IB?

The CAS Registry Number of Isoescin IB is 219944-46-4. It is also known as Escin ivb, Aescin D, Isoescin ib (constituent of horse chestnut).

What is the molecular formula and molecular weight of Isoescin IB?

Isoescin IB has the molecular formula C55H86O24 and a molecular weight of 1131.3 g/mol.

What is Isoescin IB used for?

Isoescin IB is supplied as a characterised reference material related to Escin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Isoescin IB can I order?

We supply Isoescin IB in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Isoescin IB?

Yes. Every lot of Isoescin IB is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Isoescin IB be shipped internationally?

Yes. Isoescin IB is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.