Isonitrosoacetophenone

Name: Isonitrosoacetophenone
Brand: Vaqora Chemicals
SKU: VQ-050636

About Isonitrosoacetophenone

Listed under CAS 532-54-7, Isonitrosoacetophenone is a nitrosamine impurity of Acetophenone available from Vaqora Chemicals. With the molecular formula C8H7NO2, it has a molar mass of 149.15 g/mol. The IUPAC name is (2E)-2-hydroxyimino-1-phenylethanone. It is also known as 2-Isonitrosoacetophenone or Phenylglyoxal aldoxime.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Laboratories use this nitrosamine standard to develop and validate highly sensitive LC-MS/MS methods, to confirm limits of detection and to document nitrosamine risk assessments in regulatory submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Isonitrosoacetophenone is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Acetophenone

View every impurity, metabolite and intermediate we list for Acetophenone.

Acetophenone impurities

Specifications & identifiers

Chemical identifiers
Product name	Isonitrosoacetophenone
Catalogue No.	VQ-050636
CAS Number	532-54-7
IUPAC name	(2E)-2-hydroxyimino-1-phenylethanone
Molecular formula	C₈H₇NO₂
Molecular weight	149.15 g/mol
Exact mass	149.0477
Grade	Reference Standard
HSN code	38229090
InChIKey	MLNKXLRYCLKJSS-RMKNXTFCSA-N
SMILES	C1=CC=C(C=C1)C(=O)/C=N/O
PubChem CID	9566037

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	1 / 3
TPSA	49.7 Å²
Synonyms	2-Isonitrosoacetophenone, Phenylglyoxal aldoxime, Phenylglyoxal 2-oxime, Phenylglyoxal monoxime, Glyoxal, phenyl-, 2-oxime, Benzeneacetaldehyde, alpha-oxo-, aldoxime, 2-oxo-2-phenylacetaldehyde oxime, 2-Hydroxyiminoacetophenone, Acetophenone, 2-hydroxyimino-, 2-(Hydroxyimino)acetophenone, (2E)-2-(N-hydroxyimino)-1-phenylethan-1-one, 2-(hydroxyimino)-1-phenylethan-1-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Isonitrosoacetophenone?

The CAS Registry Number of Isonitrosoacetophenone is 532-54-7. It is also known as 2-Isonitrosoacetophenone, Phenylglyoxal aldoxime, Phenylglyoxal 2-oxime.

What is the molecular formula and molecular weight of Isonitrosoacetophenone?

Isonitrosoacetophenone has the molecular formula C8H7NO2 and a molecular weight of 149.15 g/mol. Its IUPAC name is (2E)-2-hydroxyimino-1-phenylethanone.

What is Isonitrosoacetophenone used for?

Isonitrosoacetophenone is supplied as a characterised reference material related to Acetophenone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Isonitrosoacetophenone can I order?

We supply Isonitrosoacetophenone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Isonitrosoacetophenone?

Yes. Every lot of Isonitrosoacetophenone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Isonitrosoacetophenone be shipped internationally?

Yes. Isonitrosoacetophenone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.