Isoxazole-4-carboxylic acid

Name: Isoxazole-4-carboxylic acid
Brand: Vaqora Chemicals
SKU: VQ-051218

About Isoxazole-4-carboxylic acid

Listed under CAS 6436-62-0, Isoxazole-4-carboxylic acid is a process intermediate or related compound of Tretinoin available from Vaqora Chemicals. The compound has the formula C4H3NO3, corresponding to a molecular weight of 113.07 g/mol. The IUPAC name is 1,2-oxazole-4-carboxylic acid. Alternative names: 4-Isoxazolecarboxylic acid and Isooxazole-4-carboxylic acid.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Tretinoin, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Isoxazole-4-carboxylic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Tretinoin

View every impurity, metabolite and intermediate we list for Tretinoin.

Tretinoin impurities

Specifications & identifiers

Chemical identifiers
Product name	Isoxazole-4-carboxylic acid
Catalogue No.	VQ-051218
CAS Number	6436-62-0
IUPAC name	1,2-oxazole-4-carboxylic acid
Molecular formula	C₄H₃NO₃
Molecular weight	113.07 g/mol
Exact mass	113.0113
HSN code	2933
InChIKey	LYPXTDXYEQEIIN-UHFFFAOYSA-N
SMILES	C1=C(C=NO1)C(=O)O
PubChem CID	3014488

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.1
H-bond donors / acceptors	1 / 4
TPSA	63.3 Å²
Synonyms	4-Isoxazolecarboxylic acid, Isooxazole-4-carboxylic acid, 4-carboxy isoxazole, isoxazole-4-carboxylic acid, AldrichCPR, 4-Carboxyisoxazole, 1,2-Oxazole-4-carboxylic acid, 4-Carboxy-1,2-oxazole

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Isoxazole-4-carboxylic acid?

The CAS Registry Number of Isoxazole-4-carboxylic acid is 6436-62-0. It is also known as 4-Isoxazolecarboxylic acid, Isooxazole-4-carboxylic acid, 4-carboxy isoxazole.

What is the molecular formula and molecular weight of Isoxazole-4-carboxylic acid?

Isoxazole-4-carboxylic acid has the molecular formula C4H3NO3 and a molecular weight of 113.07 g/mol. Its IUPAC name is 1,2-oxazole-4-carboxylic acid.

What is Isoxazole-4-carboxylic acid used for?

Isoxazole-4-carboxylic acid is supplied as a characterised reference material related to Tretinoin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Isoxazole-4-carboxylic acid can I order?

We supply Isoxazole-4-carboxylic acid, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Isoxazole-4-carboxylic acid?

Yes. Every lot of Isoxazole-4-carboxylic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Isoxazole-4-carboxylic acid be shipped internationally?

Yes. Isoxazole-4-carboxylic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.