Istradefylline

Name: Istradefylline
Brand: Vaqora Chemicals
SKU: VQ-026246

About Istradefylline

Istradefylline is a high-purity reference standard of Istradefylline carrying the CAS registry number 155270-99-8. Its molecular formula is C20H24N4O4 and its molecular weight is 384.4 g/mol. Systematically, it is named 8-[(E)-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methylpurine-2,6-dione. Alternative names: Istradefylline (KW-6002) and Istradefyline.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Istradefylline standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Istradefylline

View every impurity, metabolite and intermediate we list for Istradefylline.

Istradefylline impurities

Specifications & identifiers

Chemical identifiers
Product name	Istradefylline
Catalogue No.	VQ-026246
CAS Number	155270-99-8
IUPAC name	8-[(E)-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methylpurine-2,6-dione
Molecular formula	C₂₀H₂₄N₄O₄
Molecular weight	384.4 g/mol
Exact mass	384.1798
Grade	Reference Standard
HSN code	38229090
InChIKey	IQVRBWUUXZMOPW-PKNBQFBNSA-N
SMILES	CCN1C2=C(C(=O)N(C1=O)CC)N(C(=N2)/C=C/C3=CC(=C(C=C3)OC)OC)C
PubChem CID	5311037

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	0 / 5
TPSA	76.9 Å²
Synonyms	(E)-8-(3,4-Dimethoxystyryl)-1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione, 8-((E)-2-(3,4-dimethoxyphenyl)ethenyl)-1,3-diethyl-7-methylpurine-2,6-dione, 8-(2-(3,4-dimethoxyphenyl)ethenyl)-1,3-diethyl-3,7-dihydro-7-methyl-1H-purine-2,6-dione, 8-[(E)-2-(3,4-Dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methyl-purine-2,6 -dione, (E)-8-(3,4-Dimethoxystyryl)-1,3-diethyl-7-methyl-1H-purine-2,6(3H,7H)-dione, (E)-8-(3,4-Dimethoxystyryl)-1,3-diethyl-7-methylxanthine, Istradefylline (KW-6002), 8-[(~{E})-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methyl-purine-2,6-dione, Istradefyline, Istradefyline - Bio-X trade mark

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Istradefylline?

The CAS Registry Number of Istradefylline is 155270-99-8. It is also known as (E)-8-(3,4-Dimethoxystyryl)-1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione, 8-((E)-2-(3,4-dimethoxyphenyl)ethenyl)-1,3-diethyl-7-methylpurine-2,6-dione, 8-(2-(3,4-dimethoxyphenyl)ethenyl)-1,3-diethyl-3,7-dihydro-7-methyl-1H-purine-2,6-dione.

What is the molecular formula and molecular weight of Istradefylline?

Istradefylline has the molecular formula C20H24N4O4 and a molecular weight of 384.4 g/mol. Its IUPAC name is 8-[(E)-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methylpurine-2,6-dione.

What is Istradefylline used for?

Istradefylline is supplied as a characterised reference material related to Istradefylline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Istradefylline can I order?

We supply Istradefylline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Istradefylline?

Yes. Every lot of Istradefylline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Istradefylline be shipped internationally?

Yes. Istradefylline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.