Itraconazole Methoxy Triazolone Impurity

Name: Itraconazole Methoxy Triazolone Impurity
Brand: Vaqora Chemicals
SKU: VQ-031312

About Itraconazole Methoxy Triazolone Impurity

Vaqora Chemicals supplies Itraconazole Methoxy Triazolone Impurity, an impurity of Itraconazole registered under CAS number 74853-07-9. The compound has the formula C19H21N5O2, corresponding to a molecular weight of 351.4 g/mol. Its systematic (IUPAC) name is 4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-1H-1,2,4-triazol-5-one.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Itraconazole, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Itraconazole Methoxy Triazolone Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Itraconazole

View every impurity, metabolite and intermediate we list for Itraconazole.

Itraconazole impurities

Specifications & identifiers

Chemical identifiers
Product name	Itraconazole Methoxy Triazolone Impurity
Catalogue No.	VQ-031312
CAS Number	74853-07-9
IUPAC name	4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-1H-1,2,4-triazol-5-one
Molecular formula	C₁₉H₂₁N₅O₂
Molecular weight	351.4 g/mol
Exact mass	351.1695
Grade	Reference Standard
HSN code	38229090
InChIKey	SEHQVBVJJRRRSG-UHFFFAOYSA-N
SMILES	COC1=CC=C(C=C1)N2CCN(CC2)C3=CC=C(C=C3)N4C=NNC4=O
PubChem CID	4246597

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	1 / 5
TPSA	60.4 Å²
Synonyms	2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1- piperazinyl]phenyl]-3H-1,2,4-triazol-3-one, 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one, 2,4-Dihydro-4-(4-(4-(4-methoxyphenyl)piperazin-1-yl)phenyl)-3H-1,2,4-triazol-3-one, 2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one, 4-(4-(4-(4-Methoxy-phenyl)-piperazin-1-yl)-phenyl)-2,4-dihydro-[1,2,4]triazol-3-one, 4-{[4-(4-Methyloxyphenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one, 4-{4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one, 4-{4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one, 2,4-dihydro-4-{4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl}-3H-1,2,4-triazol-3-one, 4-(4-(4-(4-methoxyphenyl)piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one, 4-[4-[4-(4-Methoxyphenyl)piperazin-1-yl]phenyl]-1H-1,2,4-triazol-5(4H)-one, 4-[4-[4-[4-Methoxyphenyl]piperazin-1-yl]phenyl]-2,4-dihydro-3H-1,2,4-triazol-3-one

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Itraconazole Methoxy Triazolone Impurity?

The CAS Registry Number of Itraconazole Methoxy Triazolone Impurity is 74853-07-9. It is also known as 2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1- piperazinyl]phenyl]-3H-1,2,4-triazol-3-one, 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one, 2,4-Dihydro-4-(4-(4-(4-methoxyphenyl)piperazin-1-yl)phenyl)-3H-1,2,4-triazol-3-one.

What is the molecular formula and molecular weight of Itraconazole Methoxy Triazolone Impurity?

Itraconazole Methoxy Triazolone Impurity has the molecular formula C19H21N5O2 and a molecular weight of 351.4 g/mol. Its IUPAC name is 4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-1H-1,2,4-triazol-5-one.

What is Itraconazole Methoxy Triazolone Impurity used for?

Itraconazole Methoxy Triazolone Impurity is supplied as a characterised reference material related to Itraconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Itraconazole Methoxy Triazolone Impurity can I order?

We supply Itraconazole Methoxy Triazolone Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Itraconazole Methoxy Triazolone Impurity?

Yes. Every lot of Itraconazole Methoxy Triazolone Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Itraconazole Methoxy Triazolone Impurity be shipped internationally?

Yes. Itraconazole Methoxy Triazolone Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.