L-DOPA Methyl Ester Hydrochloride

Name: L-DOPA Methyl Ester Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-038001

About L-DOPA Methyl Ester Hydrochloride

Listed under CAS 1421-65-4, L-DOPA Methyl Ester Hydrochloride is a process intermediate or related compound of Levodopa available from Vaqora Chemicals. Formula C10H14ClNO4, molecular weight 247.67 g/mol. Common synonyms include Melevodopa hydrochloride and levodopa methyl ester hydrochloride.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Levodopa, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, L-DOPA Methyl Ester Hydrochloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Levodopa

View every impurity, metabolite and intermediate we list for Levodopa.

Levodopa impurities

Specifications & identifiers

Chemical identifiers
Product name	L-DOPA Methyl Ester Hydrochloride
Catalogue No.	VQ-038001
CAS Number	1421-65-4
IUPAC name	methyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate;hydrochloride
Molecular formula	C₁₀H₁₄ClNO₄
Molecular weight	247.67 g/mol
Exact mass	247.0611
HSN code	2933
InChIKey	WFGNJLMSYIJWII-FJXQXJEOSA-N
SMILES	COC(=O)[C@H](CC1=CC(=C(C=C1)O)O)N.Cl
PubChem CID	10131132

Physical properties
Physical form	Solid
H-bond donors / acceptors	4 / 5
TPSA	92.8 Å²
Synonyms	(S)-Methyl 2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride, Melevodopa hydrochloride, L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride (1:1), levodopa methyl ester hydrochloride, L-Dopa Me ester hydrochloride, L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride, Alanine, 3-(3,4-dihydroxyphenyl)-, methyl ester, hydrochloride, l-, 3,4-Dihydroxyphenyl-l-alanine methyl ester hydrochloride, Methyl l-3-(3,4-dihydroxyphenyl)alaninate hydrochloride, Alanine, 3-(3,4-dihydroxyphenyl)-, methyl ester, hydrochloride, L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride, Methyl L-DOPA hydrochloride

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of L-DOPA Methyl Ester Hydrochloride?

The CAS Registry Number of L-DOPA Methyl Ester Hydrochloride is 1421-65-4. It is also known as (S)-Methyl 2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride, Melevodopa hydrochloride, L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride (1:1).

What is the molecular formula and molecular weight of L-DOPA Methyl Ester Hydrochloride?

L-DOPA Methyl Ester Hydrochloride has the molecular formula C10H14ClNO4 and a molecular weight of 247.67 g/mol.

What is L-DOPA Methyl Ester Hydrochloride used for?

L-DOPA Methyl Ester Hydrochloride is supplied as a characterised reference material related to Levodopa. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of L-DOPA Methyl Ester Hydrochloride can I order?

We supply L-DOPA Methyl Ester Hydrochloride, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with L-DOPA Methyl Ester Hydrochloride?

Yes. Every lot of L-DOPA Methyl Ester Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can L-DOPA Methyl Ester Hydrochloride be shipped internationally?

Yes. L-DOPA Methyl Ester Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.