L-Isoleucic acid

Name: L-Isoleucic acid
Brand: Vaqora Chemicals
SKU: VQ-032374

About L-Isoleucic acid

L-Isoleucic acid (CAS 488-15-3) is a metabolite or degradation product of Allopurinol offered by Vaqora Chemicals. The compound has the formula C6H12O3, corresponding to a molecular weight of 132.16 g/mol. Its systematic (IUPAC) name is 2-hydroxy-3-methylpentanoic acid. It is also known as 2-Hydroxy-3-methylvaleric acid or alpha-hydroxy-beta-methylvaleric acid.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Analytical teams use this compound to identify metabolites and degradants of Allopurinol, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, L-Isoleucic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Allopurinol

View every impurity, metabolite and intermediate we list for Allopurinol.

Allopurinol impurities

Specifications & identifiers

Chemical identifiers
Product name	L-Isoleucic acid
Catalogue No.	VQ-032374
CAS Number	488-15-3
IUPAC name	2-hydroxy-3-methylpentanoic acid
Molecular formula	C₆H₁₂O₃
Molecular weight	132.16 g/mol
Exact mass	132.0786
Grade	Reference Standard
HSN code	38229090
InChIKey	RILPIWOPNGRASR-UHFFFAOYSA-N
SMILES	CCC(C)C(C(=O)O)O
PubChem CID	164623

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	2 / 3
TPSA	57.5 Å²
Synonyms	2-Hydroxy-3-methylvaleric acid, alpha-hydroxy-beta-methylvaleric acid, alpha-hydroxy-3-methylpentanoic acid, Pentanoic acid, 2-hydroxy-3-methyl-, 2-Hydroxy-3-methylpentanoic Acid (Mixture of Diastereomers), 2-hydroxy-3-methylpentanoicacid, (2R,3R)-2-hydroxy-3-methyl-pentanoic acid, 2-Hydroxy-3-Methylpentadioic Acid, alpha-hydroxy-beta-methylpentanoic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of L-Isoleucic acid?

The CAS Registry Number of L-Isoleucic acid is 488-15-3. It is also known as 2-Hydroxy-3-methylvaleric acid, alpha-hydroxy-beta-methylvaleric acid, alpha-hydroxy-3-methylpentanoic acid.

What is the molecular formula and molecular weight of L-Isoleucic acid?

L-Isoleucic acid has the molecular formula C6H12O3 and a molecular weight of 132.16 g/mol. Its IUPAC name is 2-hydroxy-3-methylpentanoic acid.

What is L-Isoleucic acid used for?

L-Isoleucic acid is supplied as a characterised reference material related to Allopurinol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of L-Isoleucic acid can I order?

We supply L-Isoleucic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with L-Isoleucic acid?

Yes. Every lot of L-Isoleucic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can L-Isoleucic acid be shipped internationally?

Yes. L-Isoleucic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.