L-Menthyl 2,2-Dihydroxyacetate

Name: L-Menthyl 2,2-Dihydroxyacetate
Brand: Vaqora Chemicals
SKU: VQ-027231

About L-Menthyl 2,2-Dihydroxyacetate

Vaqora Chemicals supplies L-Menthyl 2,2-Dihydroxyacetate, an impurity of Lamivudine registered under CAS number 111969-64-3. The compound has the formula C12H22O4, corresponding to a molecular weight of 230.3 g/mol. Its systematic (IUPAC) name is [(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl] 2,2-dihydroxyacetate. It is also known as (-)-Menthyl 2,2-Dihydroxyacetate or 2,2-Dihydroxyacetic acid, (-)-menthyl ester.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Lamivudine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies L-Menthyl 2,2-Dihydroxyacetate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Lamivudine

View every impurity, metabolite and intermediate we list for Lamivudine.

Lamivudine impurities

Specifications & identifiers

Chemical identifiers
Product name	L-Menthyl 2,2-Dihydroxyacetate
Catalogue No.	VQ-027231
CAS Number	111969-64-3
IUPAC name	[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl] 2,2-dihydroxyacetate
Molecular formula	C₁₂H₂₂O₄
Molecular weight	230.3 g/mol
Exact mass	230.1518
Grade	Reference Standard
HSN code	38229090
InChIKey	BWZMJRSMHQDFIT-KXUCPTDWSA-N
SMILES	C[C@@H]1CC[C@H]([C@@H](C1)OC(=O)C(O)O)C(C)C
PubChem CID	7373179

Physical properties
Physical form	Solid
LogP (XLogP3)	2.4
H-bond donors / acceptors	2 / 4
TPSA	66.8 Å²
Synonyms	2S-isopropyl-5R-methyl-1R-cyclohexyl 2,2-dihydroxyacetate, (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl 2,2-dihydroxyacetate, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 2,2-Dihydroxyacetate, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl-2,2-dihydroxyacetate, (-)-Menthyl 2,2-Dihydroxyacetate, 2,2-Dihydroxyacetic Acid (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl Ester, 2,2-Dihydroxyacetic acid, (-)-menthyl ester, 5-Methyl-2-(propan-2-yl)cyclohexyl dihydroxyacetate, D,L-2-Isopropyl-5-methylcyclohexyl 2,2-dihydroxyacetate, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl dihydroxyacetate, (1R,2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexyl dihydroxyacetate, rel-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl2,2-dihydroxyacetate

Safety & hazard information (GHS)

Corrosive

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H318Causes serious eye damage
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P260, P264 + P265, P273, P280, P305 + P354 + P338, P317, P319, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of L-Menthyl 2,2-Dihydroxyacetate?

The CAS Registry Number of L-Menthyl 2,2-Dihydroxyacetate is 111969-64-3. It is also known as 2S-isopropyl-5R-methyl-1R-cyclohexyl 2,2-dihydroxyacetate, (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl 2,2-dihydroxyacetate, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 2,2-Dihydroxyacetate.

What is the molecular formula and molecular weight of L-Menthyl 2,2-Dihydroxyacetate?

L-Menthyl 2,2-Dihydroxyacetate has the molecular formula C12H22O4 and a molecular weight of 230.3 g/mol. Its IUPAC name is [(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl] 2,2-dihydroxyacetate.

What is L-Menthyl 2,2-Dihydroxyacetate used for?

L-Menthyl 2,2-Dihydroxyacetate is supplied as a characterised reference material related to Lamivudine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of L-Menthyl 2,2-Dihydroxyacetate can I order?

We supply L-Menthyl 2,2-Dihydroxyacetate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with L-Menthyl 2,2-Dihydroxyacetate?

Yes. Every lot of L-Menthyl 2,2-Dihydroxyacetate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can L-Menthyl 2,2-Dihydroxyacetate be shipped internationally?

Yes. L-Menthyl 2,2-Dihydroxyacetate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.