L-Proline Methyl Ester Hydrochloride

Name: L-Proline Methyl Ester Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-049619

About L-Proline Methyl Ester Hydrochloride

L-Proline Methyl Ester Hydrochloride (CAS 2133-40-6) is a process intermediate or related compound of Enalapril offered by Vaqora Chemicals. The compound has the formula C6H12ClNO2, corresponding to a molecular weight of 165.62 g/mol. It is also known as Methyl L-prolinate hydrochloride or Methyl prolinate hydrochloride.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Enalapril, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies L-Proline Methyl Ester Hydrochloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Enalapril

View every impurity, metabolite and intermediate we list for Enalapril.

Enalapril impurities

Specifications & identifiers

Chemical identifiers
Product name	L-Proline Methyl Ester Hydrochloride
Catalogue No.	VQ-049619
CAS Number	2133-40-6
IUPAC name	methyl (2S)-pyrrolidine-2-carboxylate;hydrochloride
Molecular formula	C₆H₁₂ClNO₂
Molecular weight	165.62 g/mol
Exact mass	165.0557
HSN code	2933
InChIKey	HQEIPVHJHZTMDP-JEDNCBNOSA-N
SMILES	COC(=O)[C@@H]1CCCN1.Cl
PubChem CID	2733200

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 3
TPSA	38.3 Å²
Synonyms	Methyl L-prolinate hydrochloride, Methyl prolinate hydrochloride, (S)-methyl pyrrolidine-2-carboxylate Hydrochloride, Methyl L-prolinate HCl, (S)-proline methyl ester hydrochloride, methyl proline hydrochloride, (S)-pyrrolidine-2-carboxylic acid methyl ester hydrochloride, (2s)-(methoxycarbonyl)pyrrolidine hydrochloride, H-Pro-OMe.HCl, Methyl (2S)-pyrrolidine-2-carboxylate Hydrochloride, h-pro-ome hcl, L-Proline methyl ester HCl

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements: P264, P264 + P265, P280, P302 + P352, P305 + P351 + P338, P321, P332 + P317, P337 + P317, P362 + P364

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of L-Proline Methyl Ester Hydrochloride?

The CAS Registry Number of L-Proline Methyl Ester Hydrochloride is 2133-40-6. It is also known as Methyl L-prolinate hydrochloride, Methyl prolinate hydrochloride, (S)-methyl pyrrolidine-2-carboxylate Hydrochloride.

What is the molecular formula and molecular weight of L-Proline Methyl Ester Hydrochloride?

L-Proline Methyl Ester Hydrochloride has the molecular formula C6H12ClNO2 and a molecular weight of 165.62 g/mol.

What is L-Proline Methyl Ester Hydrochloride used for?

L-Proline Methyl Ester Hydrochloride is supplied as a characterised reference material related to Enalapril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of L-Proline Methyl Ester Hydrochloride can I order?

We supply L-Proline Methyl Ester Hydrochloride, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with L-Proline Methyl Ester Hydrochloride?

Yes. Every lot of L-Proline Methyl Ester Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can L-Proline Methyl Ester Hydrochloride be shipped internationally?

Yes. L-Proline Methyl Ester Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.