Lamotrigine Impurity A

Name: Lamotrigine Impurity A
Brand: Vaqora Chemicals
SKU: VQ-005127

About Lamotrigine Impurity A

Listed under CAS 252186-78-0, Lamotrigine Impurity A is an impurity of Lamotrigine available from Vaqora Chemicals. Formula C9H6Cl2N4O, molecular weight 257.07 g/mol. Systematically, it is named 3-amino-6-(2,3-dichlorophenyl)-4H-1,2,4-triazin-5-one. It is also known as 5-Desamino 5-Oxo-2,5-dihydro Lamotrigine or Lamotrigine Related Compound C.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 1 hazard statement. Review the Safety Data Sheet before use.

This Lamotrigine impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Lamotrigine

View every impurity, metabolite and intermediate we list for Lamotrigine.

Lamotrigine impurities

Specifications & identifiers

Chemical identifiers
Product name	Lamotrigine Impurity A
Catalogue No.	VQ-005127
CAS Number	252186-78-0
IUPAC name	3-amino-6-(2,3-dichlorophenyl)-4H-1,2,4-triazin-5-one
Molecular formula	C₉H₆Cl₂N₄O
Molecular weight	257.07 g/mol
Exact mass	255.9919
Grade	Reference Standard
HSN code	38229090
InChIKey	OVNGWOHWYFBGKF-UHFFFAOYSA-N
SMILES	C1=CC(=C(C(=C1)Cl)Cl)C2=NN=C(NC2=O)N
PubChem CID	135564536

Physical properties
Physical form	Solid
LogP (XLogP3)	1.7
H-bond donors / acceptors	2 / 3
TPSA	79.8 Å²
Synonyms	5-Desamino 5-Oxo-2,5-dihydro Lamotrigine, 3-Amino-6-(2,3-dichlorophenyl)-1,2,4-tryriazin-5(2H)-one, 3-Amino-6-(2,3-dichlorophenyl)-1,2,4-tryriazin-5(4H)-one, Lamotrigine Related Compound C, Lamotrigine EP Impurity A, Lamotrigine USP Related Compound C, 3-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5(4H)-one, 1,2,4-Triazin-5(2H)-one, 3-amino-6-(2,3-dichlorophenyl)-, Lamotrigine specified impurity A, 3-Amino-6-(2,3-dichlorophenyl)-1,2,4-triazin-5(2H)-one, 3-amino-6-(2,3-dichlorophenyl)-4,5-dihydro-1,2,4-triazin-5-one, 3-amino-6-(2,3-dichlorophenyl)-2H-1,2,4-triazin-5-one

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Lamotrigine Impurity A?

The CAS Registry Number of Lamotrigine Impurity A is 252186-78-0. It is also known as 5-Desamino 5-Oxo-2,5-dihydro Lamotrigine, 3-Amino-6-(2,3-dichlorophenyl)-1,2,4-tryriazin-5(2H)-one, 3-Amino-6-(2,3-dichlorophenyl)-1,2,4-tryriazin-5(4H)-one.

What is the molecular formula and molecular weight of Lamotrigine Impurity A?

Lamotrigine Impurity A has the molecular formula C9H6Cl2N4O and a molecular weight of 257.07 g/mol. Its IUPAC name is 3-amino-6-(2,3-dichlorophenyl)-4H-1,2,4-triazin-5-one.

What is Lamotrigine Impurity A used for?

Lamotrigine Impurity A is supplied as a characterised reference material related to Lamotrigine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Lamotrigine Impurity A can I order?

We supply Lamotrigine Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Lamotrigine Impurity A?

Yes. Every lot of Lamotrigine Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Lamotrigine Impurity A be shipped internationally?

Yes. Lamotrigine Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.