Larotrectinib Sulphate WS

Name: Larotrectinib Sulphate WS
Brand: Vaqora Chemicals
SKU: VQ-007526

About Larotrectinib Sulphate WS

Vaqora Chemicals supplies Larotrectinib Sulphate WS, a high-purity reference standard of Larotrectinib registered under CAS number 1223405-08-0. Its molecular formula is C21H24F2N6O6S and its molecular weight is 526.5 g/mol. Alternative names: sulfuric acid and LOXO 101 sulfate.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Larotrectinib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Larotrectinib Sulphate WS in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Larotrectinib

View every impurity, metabolite and intermediate we list for Larotrectinib.

Larotrectinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Larotrectinib Sulphate WS
Catalogue No.	VQ-007526
CAS Number	1223405-08-0
Other CAS	1223403-58-4
IUPAC name	(3S)-N-[5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]-3-hydroxypyrrolidine-1-carboxamide;sulfuric acid
Molecular formula	C₂₁H₂₄F₂N₆O₆S
Molecular weight	526.5 g/mol
Exact mass	526.1446
Grade	Reference Standard
HSN code	38229090
InChIKey	PXHANKVTFWSDSG-QLOBERJESA-N
SMILES	C1C[C@@H](N(C1)C2=NC3=C(C=NN3C=C2)NC(=O)N4CC[C@@H](C4)O)C5=C(C=CC(=C5)F)F.OS(=O)(=O)O
PubChem CID	67330085

Physical properties
Physical form	Solid
H-bond donors / acceptors	4 / 11
TPSA	169 Å²
Synonyms	sulfuric acid, LOXO 101 sulfate, Vitrakvi, Larotrectinib Sulphate, Larotrectinib sulfate, LOXO-101 sulfate, ARRY-470 sulfate, ARRY 470 Sulfate, LOXO-101 (sulfate), EX-A1981A, Vitrakvi (TN)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P264, P270, P301 + P317, P319, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Larotrectinib Sulphate WS?

The CAS Registry Number of Larotrectinib Sulphate WS is 1223405-08-0. It is also known as sulfuric acid, LOXO 101 sulfate, Vitrakvi.

What is the molecular formula and molecular weight of Larotrectinib Sulphate WS?

Larotrectinib Sulphate WS has the molecular formula C21H24F2N6O6S and a molecular weight of 526.5 g/mol.

What is Larotrectinib Sulphate WS used for?

Larotrectinib Sulphate WS is supplied as a characterised reference material related to Larotrectinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Larotrectinib Sulphate WS can I order?

We supply Larotrectinib Sulphate WS in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Larotrectinib Sulphate WS?

Yes. Every lot of Larotrectinib Sulphate WS is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Larotrectinib Sulphate WS be shipped internationally?

Yes. Larotrectinib Sulphate WS is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.