Lazertinib

Name: Lazertinib
Brand: Vaqora Chemicals
SKU: VQ-007529

About Lazertinib

Listed under CAS 1903008-80-9, Lazertinib is a high-purity reference standard of Lazertinib available from Vaqora Chemicals. With the molecular formula C30H34N8O3, it has a molar mass of 554.6 g/mol. It is also known as GNS-1480 or Lazertinib (USAN/INN).

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Lazertinib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Lazertinib

View every impurity, metabolite and intermediate we list for Lazertinib.

Lazertinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Lazertinib
Catalogue No.	VQ-007529
CAS Number	1903008-80-9
Other CAS	2411549-88-5, 2247995-38-4, 2247995-37-3, 2247995-39-5
IUPAC name	N-[5-[[4-[4-[(dimethylamino)methyl]-3-phenylpyrazol-1-yl]pyrimidin-2-yl]amino]-4-methoxy-2-morpholin-4-ylphenyl]prop-2-enamide
Molecular formula	C₃₀H₃₄N₈O₃
Molecular weight	554.6 g/mol
Exact mass	554.2754
Grade	Reference Standard
HSN code	38229090
InChIKey	RRMJMHOQSALEJJ-UHFFFAOYSA-N
SMILES	CN(C)CC1=CN(N=C1C2=CC=CC=C2)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N5CCOCC5)OC
PubChem CID	121269225

Physical properties
Physical form	Solid
LogP (XLogP3)	3.4
H-bond donors / acceptors	2 / 9
TPSA	110 Å²
Synonyms	GNS-1480, Lazertinib (USAN/INN), Lazertinib (YH25448), N-[5-[[4-[4-[(dimethylamin, EX-A1912, Compound 73 [WO2016060443A2]

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P203, P260, P261, P264, P270, P272, P273, P280, P301 + P317, P302 + P352, P318, P319, P321, P330, P333 + P317, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Lazertinib?

The CAS Registry Number of Lazertinib is 1903008-80-9. It is also known as GNS-1480, Lazertinib (USAN/INN), Lazertinib (YH25448).

What is the molecular formula and molecular weight of Lazertinib?

Lazertinib has the molecular formula C30H34N8O3 and a molecular weight of 554.6 g/mol. Its IUPAC name is N-[5-[[4-[4-[(dimethylamino)methyl]-3-phenylpyrazol-1-yl]pyrimidin-2-yl]amino]-4-methoxy-2-morpholin-4-ylphenyl]prop-2-enamide.

What is Lazertinib used for?

Lazertinib is supplied as a characterised reference material related to Lazertinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Lazertinib can I order?

We supply Lazertinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Lazertinib?

Yes. Every lot of Lazertinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Lazertinib be shipped internationally?

Yes. Lazertinib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.