Letrozole Diacid Impurity

Name: Letrozole Diacid Impurity
Brand: Vaqora Chemicals
SKU: VQ-021256

About Letrozole Diacid Impurity

Listed under CAS 1644566-39-1, Letrozole Diacid Impurity is an impurity of Letrozole available from Vaqora Chemicals. With the molecular formula C17H13N3O4, it has a molar mass of 323.3 g/mol. Its systematic (IUPAC) name is 4-[(4-carboxyphenyl)-(1,2,4-triazol-1-yl)methyl]benzoic acid. Alternative names: Letrozole Diacid and Letrozole Impurity 5.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Letrozole impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Letrozole

View every impurity, metabolite and intermediate we list for Letrozole.

Letrozole impurities

Specifications & identifiers

Chemical identifiers
Product name	Letrozole Diacid Impurity
Catalogue No.	VQ-021256
CAS Number	1644566-39-1
IUPAC name	4-[(4-carboxyphenyl)-(1,2,4-triazol-1-yl)methyl]benzoic acid
Molecular formula	C₁₇H₁₃N₃O₄
Molecular weight	323.3 g/mol
Exact mass	323.0906
Grade	Reference Standard
HSN code	38229090
InChIKey	OMYQMDBEDMTHOJ-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1C(C2=CC=C(C=C2)C(=O)O)N3C=NC=N3)C(=O)O
PubChem CID	145710611

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	2 / 6
TPSA	105 Å²
Synonyms	Letrozole Diacid, 4,4'-((1H-1,2,4-Triazol-1-yl)methylene)dibenzoic Acid, 4-((4-carboxyphenyl)-(1,2,4-triazol-1-yl)methyl)benzoic acid, Letrozole Impurity 5, 4,4'-(1H-1,2,4-Triazol-1-ylmethylene)bis[benzoic acid], 4,4'-(1h-1,2,4-triazol-1-ylmethylene)bis-benzoic acid, 4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzoic Acid, 4,4'-[(1H-1,2,4-Triazol-1-yl)methylene]dibenzoic acid, 4,4'-((1H-1,2,4-Triazol-1-yl)methylene)dibenzoicacid, 4,4'-(1h-1,2,4-triazol-1-yl)methylenebis(benzoic acid), Benzoic acid, 4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-, 4-[(4-carboxyphenyl)(1H-1,2,4-triazol-1-yl)methyl]benzoic acid

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P263, P264, P270, P280, P318, P319, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Letrozole Diacid Impurity?

The CAS Registry Number of Letrozole Diacid Impurity is 1644566-39-1. It is also known as Letrozole Diacid, 4,4'-((1H-1,2,4-Triazol-1-yl)methylene)dibenzoic Acid, 4-((4-carboxyphenyl)-(1,2,4-triazol-1-yl)methyl)benzoic acid.

What is the molecular formula and molecular weight of Letrozole Diacid Impurity?

Letrozole Diacid Impurity has the molecular formula C17H13N3O4 and a molecular weight of 323.3 g/mol. Its IUPAC name is 4-[(4-carboxyphenyl)-(1,2,4-triazol-1-yl)methyl]benzoic acid.

What is Letrozole Diacid Impurity used for?

Letrozole Diacid Impurity is supplied as a characterised reference material related to Letrozole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Letrozole Diacid Impurity can I order?

We supply Letrozole Diacid Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Letrozole Diacid Impurity?

Yes. Every lot of Letrozole Diacid Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Letrozole Diacid Impurity be shipped internationally?

Yes. Letrozole Diacid Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.