Leucomethylene blue

Name: Leucomethylene blue
Brand: Vaqora Chemicals
SKU: VQ-031842

About Leucomethylene blue

Leucomethylene blue is an impurity of Methylene Blue carrying the CAS registry number 613-11-6. With the molecular formula C16H19N3S, it has a molar mass of 285.4 g/mol. The IUPAC name is 3-N,3-N,7-N,7-N-tetramethyl-10H-phenothiazine-3,7-diamine. It is also known as Hydromethylthionine or Leukomethylene blue.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

This Methylene Blue impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Leucomethylene blue in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Methylene Blue

View every impurity, metabolite and intermediate we list for Methylene Blue.

Methylene Blue impurities

Specifications & identifiers

Chemical identifiers
Product name	Leucomethylene blue
Catalogue No.	VQ-031842
CAS Number	613-11-6
IUPAC name	3-N,3-N,7-N,7-N-tetramethyl-10H-phenothiazine-3,7-diamine
Molecular formula	C₁₆H₁₉N₃S
Molecular weight	285.4 g/mol
Exact mass	285.13
Grade	Reference Standard
HSN code	38229090
InChIKey	QTWZICCBKBYHDM-UHFFFAOYSA-N
SMILES	CN(C)C1=CC2=C(C=C1)NC3=C(S2)C=C(C=C3)N(C)C
PubChem CID	164695

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	1 / 4
TPSA	43.8 Å²
Synonyms	Hydromethylthionine, Leukomethylene blue, Reduced methylene blue, Methylene blue, leuco, leuco-methylthioninium, N,N,N',N'-Tetramethyl-10H-phenothiazine-3,7-diamine, LMTX compound, Methylene blue leuco, Panatone, N3,N3,N7,N7-tetramethyl-10H-phenothiazine-3,7-diamine, Methylene blue leuco form, 3-N,3-N,7-N,7-N-tetramethyl-10H-phenothiazine-3,7-diamine2HBr

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Leucomethylene blue?

The CAS Registry Number of Leucomethylene blue is 613-11-6. It is also known as Hydromethylthionine, Leukomethylene blue, Reduced methylene blue.

What is the molecular formula and molecular weight of Leucomethylene blue?

Leucomethylene blue has the molecular formula C16H19N3S and a molecular weight of 285.4 g/mol. Its IUPAC name is 3-N,3-N,7-N,7-N-tetramethyl-10H-phenothiazine-3,7-diamine.

What is Leucomethylene blue used for?

Leucomethylene blue is supplied as a characterised reference material related to Methylene Blue. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Leucomethylene blue can I order?

We supply Leucomethylene blue in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Leucomethylene blue?

Yes. Every lot of Leucomethylene blue is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Leucomethylene blue be shipped internationally?

Yes. We export Leucomethylene blue worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.