Levoketoconazole

Name: Levoketoconazole
Brand: Vaqora Chemicals
SKU: VQ-031374

About Levoketoconazole

Levoketoconazole (CAS 142128-57-2) is an impurity of Ketoconazole offered by Vaqora Chemicals. The compound has the formula C26H28Cl2N4O4, corresponding to a molecular weight of 531.4 g/mol. It is also known as Nizoral or Panfungol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Ketoconazole to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Levoketoconazole in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ketoconazole

View every impurity, metabolite and intermediate we list for Ketoconazole.

Ketoconazole impurities

Specifications & identifiers

Chemical identifiers
Product name	Levoketoconazole
Catalogue No.	VQ-031374
CAS Number	142128-57-2
IUPAC name	1-[4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone
Molecular formula	C₂₆H₂₈Cl₂N₄O₄
Molecular weight	531.4 g/mol
Exact mass	530.1488
Grade	Reference Standard
HSN code	38229090
InChIKey	XMAYWYJOQHXEEK-ZEQKJWHPSA-N
SMILES	CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OC[C@@H]3CO[C@@](O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl
PubChem CID	47576

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	0 / 6
TPSA	69.1 Å²
Synonyms	Nizoral, Panfungol, Fungoral, Ketoisdin, Orifungal M, Nizoral a-D, Ketoconazol, Dandrazol, Ketopine, Daktarin gold, Daktarin intensiv, Ketosidin

Safety & hazard information (GHS)

Toxic

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P270, P273, P280, P301 + P316, P318, P319, P321, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Levoketoconazole?

The CAS Registry Number of Levoketoconazole is 142128-57-2. It is also known as Nizoral, Panfungol, Fungoral.

What is the molecular formula and molecular weight of Levoketoconazole?

Levoketoconazole has the molecular formula C26H28Cl2N4O4 and a molecular weight of 531.4 g/mol. Its IUPAC name is 1-[4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone.

What is Levoketoconazole used for?

Levoketoconazole is supplied as a characterised reference material related to Ketoconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Levoketoconazole can I order?

We supply Levoketoconazole in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Levoketoconazole?

Yes. Every lot of Levoketoconazole is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Levoketoconazole be shipped internationally?

Yes. Levoketoconazole is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.