Lifitegrast

Name: Lifitegrast
Brand: Vaqora Chemicals
SKU: VQ-031550

About Lifitegrast

Listed under CAS 1025967-78-5, Lifitegrast is a high-purity reference standard of Lifitegrast available from Vaqora Chemicals. Its molecular formula is C29H24Cl2N2O7S and its molecular weight is 615.5 g/mol. Common synonyms include SAR-1118 and SAR 1118.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Lifitegrast, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Lifitegrast in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Lifitegrast

View every impurity, metabolite and intermediate we list for Lifitegrast.

Lifitegrast impurities

Specifications & identifiers

Chemical identifiers
Product name	Lifitegrast
Catalogue No.	VQ-031550
CAS Number	1025967-78-5
IUPAC name	(2S)-2-[[2-(1-benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(3-methylsulfonylphenyl)propanoic acid
Molecular formula	C₂₉H₂₄Cl₂N₂O₇S
Molecular weight	615.5 g/mol
Exact mass	614.0681
Grade	Reference Standard
HSN code	38229090
InChIKey	JFOZKMSJYSPYLN-QHCPKHFHSA-N
SMILES	CS(=O)(=O)C1=CC=CC(=C1)C[C@@H](C(=O)O)NC(=O)C2=C(C=C3CN(CCC3=C2Cl)C(=O)C4=CC5=C(C=C4)C=CO5)Cl
PubChem CID	11965427

Physical properties
Physical form	Solid
LogP (XLogP3)	4.7
H-bond donors / acceptors	2 / 7
TPSA	142 Å²
Synonyms	SAR-1118, SAR 1118, SHP-606, Lifitegrast(SAR 1118), EX-A2582, Xiidra SAR-1118 SAR 1118

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Lifitegrast?

The CAS Registry Number of Lifitegrast is 1025967-78-5. It is also known as SAR-1118, SAR 1118, SHP-606.

What is the molecular formula and molecular weight of Lifitegrast?

Lifitegrast has the molecular formula C29H24Cl2N2O7S and a molecular weight of 615.5 g/mol. Its IUPAC name is (2S)-2-[[2-(1-benzofuran-6-carbonyl)-5,7-dichloro-3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(3-methylsulfonylphenyl)propanoic acid.

What is Lifitegrast used for?

Lifitegrast is supplied as a characterised reference material related to Lifitegrast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Lifitegrast can I order?

We supply Lifitegrast in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Lifitegrast?

Yes. Every lot of Lifitegrast is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Lifitegrast be shipped internationally?

Yes. Lifitegrast is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.