Losartan

Name: Losartan
Brand: Vaqora Chemicals
SKU: VQ-038144

About Losartan

Losartan is a high-purity reference standard of Losartan carrying the CAS registry number 114798-26-4. With the molecular formula C22H23ClN6O, it has a molar mass of 422.9 g/mol. The IUPAC name is [2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol. It is also known as Losartic or DUP-89.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Losartan, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Losartan in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Losartan

View every impurity, metabolite and intermediate we list for Losartan.

Losartan impurities

Specifications & identifiers

Chemical identifiers
Product name	Losartan
Catalogue No.	VQ-038144
CAS Number	114798-26-4
IUPAC name	[2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
Molecular formula	C₂₂H₂₃ClN₆O
Molecular weight	422.9 g/mol
Exact mass	422.1622
Grade	Reference Standard
HSN code	38229090
InChIKey	PSIFNNKUMBGKDQ-UHFFFAOYSA-N
SMILES	CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)CO)Cl
PubChem CID	3961

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	2 / 5
TPSA	92.5 Å²
Synonyms	Losartic, DUP-89, HGP-1405, (2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanol, 2-n-butyl-4-chloro-5-hydroxymethyl-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]imidazole, (2-butyl-5-chloro-3-((4-(2-(2H-tetrazol-5-yl)phenyl)phenyl)methyl)imidazol-4-yl)methanol, (2-butyl-4-chloro-1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1H-imidazol-5-yl)methanol, 2-n-butyl-4-chloro-5-hydroxymethyl-1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)imidazole, DUP 89, 2-Butyl-4-chloro-1-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]imidazole-5- methanol, [3H]losartan, [3H]-losartan

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
H360May damage fertility or the unborn child
H362May cause harm to breast-fed children
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P203, P260, P261, P263, P264, P264 + P265, P270, P271, P272, P273, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Losartan?

The CAS Registry Number of Losartan is 114798-26-4. It is also known as Losartic, DUP-89, HGP-1405.

What is the molecular formula and molecular weight of Losartan?

Losartan has the molecular formula C22H23ClN6O and a molecular weight of 422.9 g/mol. Its IUPAC name is [2-butyl-5-chloro-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol.

What is Losartan used for?

Losartan is supplied as a characterised reference material related to Losartan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Losartan can I order?

We supply Losartan in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Losartan?

Yes. Every lot of Losartan is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Losartan be shipped internationally?

Yes. Losartan is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.