Loteprednol etabonate 17-Carboxylic acid

Name: Loteprednol etabonate 17-Carboxylic acid
Brand: Vaqora Chemicals
SKU: VQ-026523

About Loteprednol etabonate 17-Carboxylic acid

Loteprednol etabonate 17-Carboxylic acid (CAS 133991-63-6) is an impurity of Prednisolone offered by Vaqora Chemicals. With the molecular formula C23H30O7, it has a molar mass of 418.5 g/mol. Alternative names: Dechloromethyl Loteprednol Etabonate.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Prednisolone, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Loteprednol etabonate 17-Carboxylic acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Prednisolone

View every impurity, metabolite and intermediate we list for Prednisolone.

Prednisolone impurities

Specifications & identifiers

Chemical identifiers
Product name	Loteprednol etabonate 17-Carboxylic acid
Catalogue No.	VQ-026523
CAS Number	133991-63-6
IUPAC name	(8S,9S,10R,11S,13S,14S,17R)-17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylic acid
Molecular formula	C₂₃H₃₀O₇
Molecular weight	418.5 g/mol
Exact mass	418.1992
Grade	Reference Standard
HSN code	38229090
InChIKey	CCMMQGHLQQKWOY-NGVSTBRYSA-N
SMILES	CCOC(=O)O[C@@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)C=C[C@]34C)O)C)C(=O)O
PubChem CID	12986112

Physical properties
Physical form	Solid
LogP (XLogP3)	2.9
H-bond donors / acceptors	2 / 7
TPSA	110 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Loteprednol etabonate 17-Carboxylic acid?

The CAS Registry Number of Loteprednol etabonate 17-Carboxylic acid is 133991-63-6. It is also known as Dechloromethyl Loteprednol Etabonate.

What is the molecular formula and molecular weight of Loteprednol etabonate 17-Carboxylic acid?

Loteprednol etabonate 17-Carboxylic acid has the molecular formula C23H30O7 and a molecular weight of 418.5 g/mol. Its IUPAC name is (8S,9S,10R,11S,13S,14S,17R)-17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylic acid.

What is Loteprednol etabonate 17-Carboxylic acid used for?

Loteprednol etabonate 17-Carboxylic acid is supplied as a characterised reference material related to Prednisolone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Loteprednol etabonate 17-Carboxylic acid can I order?

We supply Loteprednol etabonate 17-Carboxylic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Loteprednol etabonate 17-Carboxylic acid?

Yes. Every lot of Loteprednol etabonate 17-Carboxylic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Loteprednol etabonate 17-Carboxylic acid be shipped internationally?

Yes. We export Loteprednol etabonate 17-Carboxylic acid worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.