Meclizine N,N'-Dioxide

Name: Meclizine N,N'-Dioxide
Brand: Vaqora Chemicals
SKU: VQ-043219

About Meclizine N,N'-Dioxide

Listed under CAS 114624-70-3, Meclizine N,N'-Dioxide is an impurity of Meclozine available from Vaqora Chemicals. With the molecular formula C25H27ClN2O2, it has a molar mass of 422.9 g/mol. The IUPAC name is 1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]-1,4-dioxidopiperazine-1,4-diium. Alternative names: Meclizine N-Oxide (N, N'-Dioxide).

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Meclozine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Meclizine N,N'-Dioxide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Meclozine

View every impurity, metabolite and intermediate we list for Meclozine.

Meclozine impurities

Specifications & identifiers

Chemical identifiers
Product name	Meclizine N,N'-Dioxide
Catalogue No.	VQ-043219
CAS Number	114624-70-3
IUPAC name	1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]-1,4-dioxidopiperazine-1,4-diium
Molecular formula	C₂₅H₂₇ClN₂O₂
Molecular weight	422.9 g/mol
Exact mass	422.1761
Grade	Reference Standard
HSN code	38229090
InChIKey	AGPRHOVRGSVTKD-UHFFFAOYSA-N
SMILES	CC1=CC(=CC=C1)C[N+]2(CC[N+](CC2)(C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl)[O-])[O-]
PubChem CID	53641921

Physical properties
Physical form	Solid
LogP (XLogP3)	4.6
H-bond donors / acceptors	0 / 2
TPSA	36.1 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Meclizine N,N'-Dioxide?

The CAS Registry Number of Meclizine N,N'-Dioxide is 114624-70-3. It is also known as Meclizine N-Oxide (N, N'-Dioxide), 1-((4-Chlorophenyl)(phenyl)methyl)-4-(3-methylbenzyl)piperazine 1,4-Dioxide, Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-, 1,4-dioxide.

What is the molecular formula and molecular weight of Meclizine N,N'-Dioxide?

Meclizine N,N'-Dioxide has the molecular formula C25H27ClN2O2 and a molecular weight of 422.9 g/mol. Its IUPAC name is 1-[(4-chlorophenyl)-phenylmethyl]-4-[(3-methylphenyl)methyl]-1,4-dioxidopiperazine-1,4-diium.

What is Meclizine N,N'-Dioxide used for?

Meclizine N,N'-Dioxide is supplied as a characterised reference material related to Meclozine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Meclizine N,N'-Dioxide can I order?

We supply Meclizine N,N'-Dioxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Meclizine N,N'-Dioxide?

Yes. Every lot of Meclizine N,N'-Dioxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Meclizine N,N'-Dioxide be shipped internationally?

Yes. We export Meclizine N,N'-Dioxide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.