Meldrum's Acid

Name: Meldrum's Acid
Brand: Vaqora Chemicals
SKU: VQ-007564

About Meldrum's Acid

Meldrum's Acid is an API reference standard carrying the CAS registry number 2033-24-1. With the molecular formula C6H8O4, it has a molar mass of 144.12 g/mol. The IUPAC name is 2,2-dimethyl-1,3-dioxane-4,6-dione. It is also known as 2,2-Propanediol Cyclic Malonate or Cyclic Isopropylidene Malonate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this the parent drug substance standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Meldrum's Acid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Specifications & identifiers

Chemical identifiers
Product name	Meldrum's Acid
Catalogue No.	VQ-007564
CAS Number	2033-24-1
IUPAC name	2,2-dimethyl-1,3-dioxane-4,6-dione
Molecular formula	C₆H₈O₄
Molecular weight	144.12 g/mol
Exact mass	144.0423
Grade	Reference Standard
HSN code	38229090
InChIKey	GXHFUVWIGNLZSC-UHFFFAOYSA-N
SMILES	CC1(OC(=O)CC(=O)O1)C
PubChem CID	16249

Physical properties
Physical form	Solid
LogP (XLogP3)	0.6
H-bond donors / acceptors	0 / 4
TPSA	52.6 Å²
Synonyms	2,2-Propanediol Cyclic Malonate, Cyclic Isopropylidene Malonate, Isopropylidene Malonate, Meldrumic Acid, N,N-Dimethyl-1-4-aminobilidine, 1,3-Dioxane-4,6-dione, 2,2-dimethyl-, Malonic acid, cyclic isopropylidene ester, 2,2-Dimethyl-m-dioxane-4,6-dione, 2,2-Dimethyl-1,3-dioxan-4,6-dione, Meldrums acid, Malonic acid cyclic isopropylidene ester, cycl-Isopropylidene malonate

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H400Very toxic to aquatic life
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P261, P264, P264 + P265, P271, P273, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 2033-24-1

Meldrum's acid, ≥98%

CAS: 2033-24-1
Formula: C₆H₈O₄
MW: 144.12 g/mol

VQ-008848

Frequently asked questions

What is the CAS number of Meldrum's Acid?

The CAS Registry Number of Meldrum's Acid is 2033-24-1. It is also known as 2,2-Propanediol Cyclic Malonate, Cyclic Isopropylidene Malonate, Isopropylidene Malonate.

What is the molecular formula and molecular weight of Meldrum's Acid?

Meldrum's Acid has the molecular formula C6H8O4 and a molecular weight of 144.12 g/mol. Its IUPAC name is 2,2-dimethyl-1,3-dioxane-4,6-dione.

Which grade and pack sizes of Meldrum's Acid can I order?

We supply Meldrum's Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Meldrum's Acid?

Yes. Every lot of Meldrum's Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Meldrum's Acid be shipped internationally?

Yes. Meldrum's Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.