Menadiol

Name: Menadiol
Brand: Vaqora Chemicals
SKU: VQ-049041

About Menadiol

Vaqora Chemicals supplies Menadiol, a high-purity reference standard of Paracetamol registered under CAS number 481-85-6. Formula C11H10O2, molecular weight 174.2 g/mol. Its systematic (IUPAC) name is 2-methylnaphthalene-1,4-diol. It is also known as 2-Methyl-1,4-naphthohydroquinone or 2-Methyl-1,4-naphthalenediol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Laboratories use this Paracetamol standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Paracetamol

View every impurity, metabolite and intermediate we list for Paracetamol.

Paracetamol impurities

Specifications & identifiers

Chemical identifiers
Product name	Menadiol
Catalogue No.	VQ-049041
CAS Number	481-85-6
IUPAC name	2-methylnaphthalene-1,4-diol
Molecular formula	C₁₁H₁₀O₂
Molecular weight	174.2 g/mol
Exact mass	174.0681
Grade	Reference Standard
HSN code	38229090
InChIKey	ZJTLZYDQJHKRMQ-UHFFFAOYSA-N
SMILES	CC1=C(C2=CC=CC=C2C(=C1)O)O
PubChem CID	10209

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	2 / 2
TPSA	40.5 Å²
Synonyms	2-Methyl-1,4-naphthohydroquinone, 2-Methyl-1,4-naphthalenediol, Vitamin K3H2, Dihydrovitamin K3, Reduced menadione, Methylnaphthohydroquinone, Reduced vitamin K3, 2-Methylhydronaphthoquinone, 2-Methyl-1,4-naphthoquinol, 1,4-dihydroxy-2-methylnaphthalene, Menadiol (BAN), 2-Methyl-1,4-dihydroxynaphthalene

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Menadiol?

The CAS Registry Number of Menadiol is 481-85-6. It is also known as 2-Methyl-1,4-naphthohydroquinone, 2-Methyl-1,4-naphthalenediol, Vitamin K3H2.

What is the molecular formula and molecular weight of Menadiol?

Menadiol has the molecular formula C11H10O2 and a molecular weight of 174.2 g/mol. Its IUPAC name is 2-methylnaphthalene-1,4-diol.

What is Menadiol used for?

Menadiol is supplied as a characterised reference material related to Paracetamol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Menadiol can I order?

We supply Menadiol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Menadiol?

Yes. Every lot of Menadiol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Menadiol be shipped internationally?

Yes. Menadiol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.