Metformin Impurity A

Name: Metformin Impurity A
Brand: Vaqora Chemicals
SKU: VQ-005259

About Metformin Impurity A

Vaqora Chemicals supplies Metformin Impurity A, an impurity of Metformin registered under CAS number 461-58-5. Formula C2H4N4, molecular weight 84.08 g/mol. Systematically, it is named 2-cyanoguanidine. It is also known as Dicyanandiamide or N-Cyanoguanidine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Metformin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Metformin

View every impurity, metabolite and intermediate we list for Metformin.

Metformin impurities

Specifications & identifiers

Chemical identifiers
Product name	Metformin Impurity A
Catalogue No.	VQ-005259
CAS Number	461-58-5
Other CAS	5678-96-6, 25752-57-2
IUPAC name	2-cyanoguanidine
Molecular formula	C₂H₄N₄
Molecular weight	84.08 g/mol
Exact mass	84.0436
Grade	Reference Standard
HSN code	38229090
InChIKey	QGBSISYHAICWAH-UHFFFAOYSA-N
SMILES	C(#N)N=C(N)N
PubChem CID	10005

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.2
H-bond donors / acceptors	2 / 2
TPSA	88.2 Å²
Synonyms	Dicyanandiamide, N-Cyanoguanidine, 1-Cyanoguanidine, CGNA, Dicyandiamide, Dicyanodiamide, Didin, Epicure DICY, Metformin Related Compound A USP, Metformin EP Impurity A, Pyroset DO, Dicyandiamin

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 461-58-5

Synthesis

Dicyandiamide, 98%

CAS: 461-58-5
Formula: C₂H₄N₄
MW: 84.08 g/mol

VQ-009706

Frequently asked questions

What is the CAS number of Metformin Impurity A?

The CAS Registry Number of Metformin Impurity A is 461-58-5. It is also known as Dicyanandiamide, N-Cyanoguanidine, 1-Cyanoguanidine.

What is the molecular formula and molecular weight of Metformin Impurity A?

Metformin Impurity A has the molecular formula C2H4N4 and a molecular weight of 84.08 g/mol. Its IUPAC name is 2-cyanoguanidine.

What is Metformin Impurity A used for?

Metformin Impurity A is supplied as a characterised reference material related to Metformin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Metformin Impurity A can I order?

We supply Metformin Impurity A in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Metformin Impurity A?

Yes. Every lot of Metformin Impurity A is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Metformin Impurity A be shipped internationally?

Yes. Metformin Impurity A is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.