Methyl

Name: Methyl
Brand: Vaqora Chemicals
SKU: VQ-043840

About Methyl

Vaqora Chemicals supplies Methyl, an impurity of Nintedanib registered under CAS number 1174335-83-1. The compound has the formula C20H16ClNO5, corresponding to a molecular weight of 385.8 g/mol. Systematically, it is named methyl (3E)-1-(2-chloroacetyl)-3-[methoxy(phenyl)methylidene]-2-oxoindole-6-carboxylate. Alternative names: CS-M3032.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Nintedanib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Nintedanib

View every impurity, metabolite and intermediate we list for Nintedanib.

Nintedanib impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl
Catalogue No.	VQ-043840
CAS Number	1174335-83-1
IUPAC name	methyl (3E)-1-(2-chloroacetyl)-3-[methoxy(phenyl)methylidene]-2-oxoindole-6-carboxylate
Molecular formula	C₂₀H₁₆ClNO₅
Molecular weight	385.8 g/mol
Exact mass	385.0717
Grade	Reference Standard
HSN code	38229090
InChIKey	SGESEGRPYLHYDV-ISLYRVAYSA-N
SMILES	CO/C(=C/1\C2=C(C=C(C=C2)C(=O)OC)N(C1=O)C(=O)CCl)/C3=CC=CC=C3
PubChem CID	42634135

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	0 / 5
TPSA	72.9 Å²
Synonyms	(E)-methyl 1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, Methyl (E)-1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, (Z)-methyl 1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, Methyl 1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, CS-M3032, (E)-methyl1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, methyl (3E)-1-(2-chloroacetyl)-3-[methoxy(phenyl)methylene]-2-oxo-indoline-6-carboxylate

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl?

The CAS Registry Number of Methyl is 1174335-83-1. It is also known as (E)-methyl 1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, Methyl (E)-1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate, (Z)-methyl 1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate.

What is the molecular formula and molecular weight of Methyl?

Methyl has the molecular formula C20H16ClNO5 and a molecular weight of 385.8 g/mol. Its IUPAC name is methyl (3E)-1-(2-chloroacetyl)-3-[methoxy(phenyl)methylidene]-2-oxoindole-6-carboxylate.

What is Methyl used for?

Methyl is supplied as a characterised reference material related to Nintedanib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl can I order?

We supply Methyl in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl?

Yes. Every lot of Methyl is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl be shipped internationally?

Yes. We export Methyl worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.