Methyl

Name: Methyl
Brand: Vaqora Chemicals
SKU: VQ-045123

About Methyl

Methyl (CAS 1269440-60-9) is an impurity of Encorafenib offered by Vaqora Chemicals. Formula C15H21IN6O2, molecular weight 444.27 g/mol. Its systematic (IUPAC) name is methyl N-[(2S)-1-[[4-(3-iodo-1-propan-2-ylpyrazol-4-yl)pyrimidin-2-yl]amino]propan-2-yl]carbamate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Encorafenib, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Methyl in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Encorafenib

View every impurity, metabolite and intermediate we list for Encorafenib.

Encorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl
Catalogue No.	VQ-045123
CAS Number	1269440-60-9
IUPAC name	methyl N-[(2S)-1-[[4-(3-iodo-1-propan-2-ylpyrazol-4-yl)pyrimidin-2-yl]amino]propan-2-yl]carbamate
Molecular formula	C₁₅H₂₁IN₆O₂
Molecular weight	444.27 g/mol
Exact mass	444.0771
Grade	Reference Standard
HSN code	38229090
InChIKey	VWEMYHDJVJQLKH-JTQLQIEISA-N
SMILES	C[C@@H](CNC1=NC=CC(=N1)C2=CN(N=C2I)C(C)C)NC(=O)OC
PubChem CID	51034342

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	2 / 6
TPSA	94 Å²

Safety & hazard information (GHS)

Harmful / irritant

Environmental hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H401Toxic to aquatic life
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P261, P264, P270, P272, P273, P280, P301 + P317, P302 + P352, P321, P330, P333 + P317, P362 + P364, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl?

The CAS Registry Number of Methyl is 1269440-60-9. It is also known as (S)-Methyl 1-(4-(3-iodo-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-ylamino)propan-2-ylcarbamate, Methyl (S)-[1-[[4-(3-Iodo-1-isopropyl-4-pyrazolyl)pyrimidin-2-yl]amino]-2-propyl]carbamate.

What is the molecular formula and molecular weight of Methyl?

Methyl has the molecular formula C15H21IN6O2 and a molecular weight of 444.27 g/mol. Its IUPAC name is methyl N-[(2S)-1-[[4-(3-iodo-1-propan-2-ylpyrazol-4-yl)pyrimidin-2-yl]amino]propan-2-yl]carbamate.

What is Methyl used for?

Methyl is supplied as a characterised reference material related to Encorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl can I order?

We supply Methyl in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl?

Yes. Every lot of Methyl is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl be shipped internationally?

Yes. Methyl is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.