Methyl 2-(2,3-Dichlorobenzylidene)acetoacetate 74073-22-6

Name: Methyl 2-(2,3-Dichlorobenzylidene)acetoacetate
Brand: Vaqora Chemicals
SKU: VQ-030696

About Methyl 2-(2,3-Dichlorobenzylidene)acetoacetate

Methyl 2-(2,3-Dichlorobenzylidene)acetoacetate is an impurity of Felodipine carrying the CAS registry number 74073-22-6. Its molecular formula is C12H10Cl2O3 and its molecular weight is 273.11 g/mol. Its systematic (IUPAC) name is methyl (2E)-2-[(2,3-dichlorophenyl)methylidene]-3-oxobutanoate. Alternative names: 2,3-dichlorobenzylideneacetoacetate and Methyl-2-(2,3-dichlorbenzyliden)acetoacetate.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Felodipine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Methyl 2-(2,3-Dichlorobenzylidene)acetoacetate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Felodipine

View every impurity, metabolite and intermediate we list for Felodipine.

Felodipine impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl 2-(2,3-Dichlorobenzylidene)acetoacetate
Catalogue No.	VQ-030696
CAS Number	74073-22-6
IUPAC name	methyl (2E)-2-[(2,3-dichlorophenyl)methylidene]-3-oxobutanoate
Molecular formula	C₁₂H₁₀Cl₂O₃
Molecular weight	273.11 g/mol
Exact mass	272.0007
Grade	Reference Standard
HSN code	38229090
InChIKey	QQXPSPWWWCQBFM-RMKNXTFCSA-N
SMILES	CC(=O)/C(=C\C1=C(C(=CC=C1)Cl)Cl)/C(=O)OC
PubChem CID	11821770

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	0 / 3
TPSA	43.4 Å²
Synonyms	Methyl (Z)-2-(2,3-dichlorobenzylidene)-3-oxobutanoate, Methyl (2E)-2-((2,3-dichlorophenyl)methylidene)-3-oxobutanoate, Methyl 2-(2,3-dichlorobenzylidene)-3-oxobutanoate, Methyl (E)-2-(2,3-dichlorobenzylidene)-3-oxobutanoate, Butanoic acid, 2-[(2,3-dichlorophenyl)methylene]-3-oxo-, methyl ester, 2,3-dichlorobenzylideneacetoacetate, Methyl-2-(2,3-dichlorbenzyliden)acetoacetate, methyl (2E)-2-[(2,3-dichlorophenyl)methylene]-3-oxo-butanoate, Butanoic acid, 2-[(2,3-dichlorophenyl)methylene]-3-oxo-, methyl ester, (2E)-, Methyl (2E)-2-[(2,3-dichlorophenyl)methylene]-3-oxobutanoate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl 2-(2,3-Dichlorobenzylidene)acetoacetate?

The CAS Registry Number of Methyl 2-(2,3-Dichlorobenzylidene)acetoacetate is 74073-22-6. It is also known as Methyl (Z)-2-(2,3-dichlorobenzylidene)-3-oxobutanoate, Methyl (2E)-2-((2,3-dichlorophenyl)methylidene)-3-oxobutanoate, Methyl 2-(2,3-dichlorobenzylidene)-3-oxobutanoate.

What is the molecular formula and molecular weight of Methyl 2-(2,3-Dichlorobenzylidene)acetoacetate?

Methyl 2-(2,3-Dichlorobenzylidene)acetoacetate has the molecular formula C12H10Cl2O3 and a molecular weight of 273.11 g/mol. Its IUPAC name is methyl (2E)-2-[(2,3-dichlorophenyl)methylidene]-3-oxobutanoate.

What is Methyl 2-(2,3-Dichlorobenzylidene)acetoacetate used for?

Methyl 2-(2,3-Dichlorobenzylidene)acetoacetate is supplied as a characterised reference material related to Felodipine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl 2-(2,3-Dichlorobenzylidene)acetoacetate can I order?

We supply Methyl 2-(2,3-Dichlorobenzylidene)acetoacetate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl 2-(2,3-Dichlorobenzylidene)acetoacetate?

Yes. Every lot of Methyl 2-(2,3-Dichlorobenzylidene)acetoacetate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl 2-(2,3-Dichlorobenzylidene)acetoacetate be shipped internationally?

Yes. Methyl 2-(2,3-Dichlorobenzylidene)acetoacetate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.