Methyl 2-naphthoate

Name: Methyl 2-naphthoate
Brand: Vaqora Chemicals
SKU: VQ-047336

About Methyl 2-naphthoate

Listed under CAS 2459-25-8, Methyl 2-naphthoate is an impurity of Adapalene available from Vaqora Chemicals. The compound has the formula C12H10O2, corresponding to a molecular weight of 186.21 g/mol. Systematically, it is named methyl naphthalene-2-carboxylate. It is also known as 2-Naphthalenecarboxylic acid, methyl ester or Methyl 2-naphthalenecarboxylate.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Adapalene, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Methyl 2-naphthoate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Adapalene

View every impurity, metabolite and intermediate we list for Adapalene.

Adapalene impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl 2-naphthoate
Catalogue No.	VQ-047336
CAS Number	2459-25-8
IUPAC name	methyl naphthalene-2-carboxylate
Molecular formula	C₁₂H₁₀O₂
Molecular weight	186.21 g/mol
Exact mass	186.0681
Grade	Reference Standard
HSN code	38229090
InChIKey	IODOXLXFXNATGI-UHFFFAOYSA-N
SMILES	COC(=O)C1=CC2=CC=CC=C2C=C1
PubChem CID	137605

Physical properties
Physical form	Solid
LogP (XLogP3)	3.6
H-bond donors / acceptors	0 / 2
TPSA	26.3 Å²
Synonyms	2-Naphthalenecarboxylic acid, methyl ester, Methyl 2-naphthalenecarboxylate, 2-Naphthoic acid, methyl ester, 2-Naphthalenecarboxylic acid methyl ester, naphthalene-2-carboxylic acid methyl ester

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl 2-naphthoate?

The CAS Registry Number of Methyl 2-naphthoate is 2459-25-8. It is also known as 2-Naphthalenecarboxylic acid, methyl ester, Methyl 2-naphthalenecarboxylate, 2-Naphthoic acid, methyl ester.

What is the molecular formula and molecular weight of Methyl 2-naphthoate?

Methyl 2-naphthoate has the molecular formula C12H10O2 and a molecular weight of 186.21 g/mol. Its IUPAC name is methyl naphthalene-2-carboxylate.

What is Methyl 2-naphthoate used for?

Methyl 2-naphthoate is supplied as a characterised reference material related to Adapalene. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl 2-naphthoate can I order?

We supply Methyl 2-naphthoate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl 2-naphthoate?

Yes. Every lot of Methyl 2-naphthoate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl 2-naphthoate be shipped internationally?

Yes. Methyl 2-naphthoate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.