Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate
Synonyms: Methyl 4-(acetylamino)-5-chloro-2,3-dihydro-1-benzofuran-7-carboxylate · 7-Benzofurancarboxylic acid, 4-(acetylamino)-5-chloro-2,3-dihydro-, methyl ester · Methyl 4-(acetylamino)-5-chloro-2,3-dihydrobenzofuran-7-carboxylate · Prucalopride intermediateA
Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate (CAS 143878-29-9) – Prucalopride impurity standard. C12H12ClNO4, MW 269.68. COA included.
About Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate
Vaqora Chemicals supplies Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate, an impurity of Prucalopride registered under CAS number 143878-29-9. Formula C12H12ClNO4, molecular weight 269.68 g/mol. The IUPAC name is methyl 4-acetamido-5-chloro-2,3-dihydro-1-benzofuran-7-carboxylate. It is also known as Prucalopride intermediateA or Prucalopride Succinate interMediate A.
The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.
Pharmaceutical QC and development laboratories use this impurity standard of Prucalopride to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.
Typical applications
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Industries
View every impurity, metabolite and intermediate we list for Prucalopride.
Prucalopride impuritiesSpecifications & identifiers
| Product name | Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate |
|---|---|
| Catalogue No. | VQ-041751 |
| CAS Number | 143878-29-9 |
| IUPAC name | methyl 4-acetamido-5-chloro-2,3-dihydro-1-benzofuran-7-carboxylate |
| Molecular formula | C12H12ClNO4 |
| Molecular weight | 269.68 g/mol |
| Exact mass | 269.0455 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | LCPRNYGRYCDBOM-UHFFFAOYSA-N |
| SMILES | CC(=O)NC1=C(C=C(C2=C1CCO2)C(=O)OC)Cl |
| PubChem CID | 10635698 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 1.6 |
| H-bond donors / acceptors | 1 / 4 |
| TPSA | 64.6 Ų |
| Synonyms | Methyl 4-(acetylamino)-5-chloro-2,3-dihydro-1-benzofuran-7-carboxylate, 7-Benzofurancarboxylic acid, 4-(acetylamino)-5-chloro-2,3-dihydro-, methyl ester, Methyl 4-(acetylamino)-5-chloro-2,3-dihydrobenzofuran-7-carboxylate, Prucalopride intermediateA, Methyl 4-acetamido-5-chloro-2,3-dihydrobenzo[b]furan-7-carboxylate, Prucalopride Succinate interMediate A, 4-acetamidoamino-5-chlorobenzofuran-7-carboxylic acid methyl ester, Methyl4-(acetylaMino)-5-chloro-2,3-dihydro-1-benzofuran-7-carboxylate |
Safety & hazard information (GHS)
Signal word: Warning
Hazard statements
H317May cause an allergic skin reaction
Precautionary statements: P261, P272, P280, P302 + P352, P321, P333 + P317, P362 + P364, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate?
The CAS Registry Number of Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate is 143878-29-9. It is also known as Methyl 4-(acetylamino)-5-chloro-2,3-dihydro-1-benzofuran-7-carboxylate, 7-Benzofurancarboxylic acid, 4-(acetylamino)-5-chloro-2,3-dihydro-, methyl ester, Methyl 4-(acetylamino)-5-chloro-2,3-dihydrobenzofuran-7-carboxylate.
What is the molecular formula and molecular weight of Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate?
Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate has the molecular formula C12H12ClNO4 and a molecular weight of 269.68 g/mol. Its IUPAC name is methyl 4-acetamido-5-chloro-2,3-dihydro-1-benzofuran-7-carboxylate.
What is Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate used for?
Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate is supplied as a characterised reference material related to Prucalopride. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate can I order?
We supply Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate?
Yes. Every lot of Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate be shipped internationally?
Yes. Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about Methyl 4-acetamido-5-chloro-2,3-dihydrobenzofuran-7-carboxylate
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