Methyl 4-methoxycarbonylbenzoylacetate

Name: Methyl 4-methoxycarbonylbenzoylacetate
Brand: Vaqora Chemicals
SKU: VQ-048700

About Methyl 4-methoxycarbonylbenzoylacetate

Vaqora Chemicals supplies Methyl 4-methoxycarbonylbenzoylacetate, an impurity of Iptacopan registered under CAS number 22027-52-7. With the molecular formula C12H12O5, it has a molar mass of 236.22 g/mol. Systematically, it is named methyl 4-(3-methoxy-3-oxopropanoyl)benzoate. Alternative names: dimethyl p-(carboxyacetyl)benzoate and methyl 4-(3-methoxy-3-oxo-propanoyl)benzoate.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 6 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Iptacopan, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Methyl 4-methoxycarbonylbenzoylacetate is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Iptacopan

View every impurity, metabolite and intermediate we list for Iptacopan.

Iptacopan impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl 4-methoxycarbonylbenzoylacetate
Catalogue No.	VQ-048700
CAS Number	22027-52-7
IUPAC name	methyl 4-(3-methoxy-3-oxopropanoyl)benzoate
Molecular formula	C₁₂H₁₂O₅
Molecular weight	236.22 g/mol
Exact mass	236.0685
Grade	Reference Standard
HSN code	38229090
InChIKey	PAGMDUGVIOXELP-UHFFFAOYSA-N
SMILES	COC(=O)CC(=O)C1=CC=C(C=C1)C(=O)OC
PubChem CID	3864207

Physical properties
Physical form	Solid
LogP (XLogP3)	1.5
H-bond donors / acceptors	0 / 5
TPSA	69.7 Å²
Synonyms	4-(methoxycarbonyl)-beta-oxoBenzenepropanoic acid methyl ester, 4-(2-Methoxycarbonyl-acetyl)-benzoic acid methyl ester, dimethyl p-(carboxyacetyl)benzoate, methyl 4-(3-methoxy-3-oxo-propanoyl)benzoate, 4-methoxycarbonylbenzoyl acetic acid methyl ester, methyl 3-[4-(methoxycarbonyl)phenyl]-3-oxopropanoate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl 4-methoxycarbonylbenzoylacetate?

The CAS Registry Number of Methyl 4-methoxycarbonylbenzoylacetate is 22027-52-7. It is also known as 4-(methoxycarbonyl)-beta-oxoBenzenepropanoic acid methyl ester, 4-(2-Methoxycarbonyl-acetyl)-benzoic acid methyl ester, dimethyl p-(carboxyacetyl)benzoate.

What is the molecular formula and molecular weight of Methyl 4-methoxycarbonylbenzoylacetate?

Methyl 4-methoxycarbonylbenzoylacetate has the molecular formula C12H12O5 and a molecular weight of 236.22 g/mol. Its IUPAC name is methyl 4-(3-methoxy-3-oxopropanoyl)benzoate.

What is Methyl 4-methoxycarbonylbenzoylacetate used for?

Methyl 4-methoxycarbonylbenzoylacetate is supplied as a characterised reference material related to Iptacopan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl 4-methoxycarbonylbenzoylacetate can I order?

We supply Methyl 4-methoxycarbonylbenzoylacetate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl 4-methoxycarbonylbenzoylacetate?

Yes. Every lot of Methyl 4-methoxycarbonylbenzoylacetate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl 4-methoxycarbonylbenzoylacetate be shipped internationally?

Yes. Methyl 4-methoxycarbonylbenzoylacetate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.